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Evidence found and GRADE certainty

48 questions · 53 findings · 8 reviews · Oral Health · All outcomes

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No studies found 0 · 0%GRADE not reported 44 · 83%Very low 6 · 11.3%Low 2 · 3.8%Moderate 1 · 1.9%High 0 · 0%

Women who experienced preterm birth vs Women who did not experience preterm birth (term)

Decayed, missing, filled surfaces (DMFS) · pregnant women

Women who experienced preterm birth did not have a significantly different DMFS than those who did not (mean difference -0.15, 95% CI -3.40 to 3.09; 3 studies; I2=89%); certainty of evidence not graded.

1 finding from 1 review
  • Dental caries and preterm birth: a systematic review and meta-analysis. 2018 All outcomes
    Pregnant women assessed around delivery in observational studies across multiple countries (Mexico, Malawi, India, France, Jordan, Finland, Tanzania); mostly retrospective cohort and case-control designs
    MD -0.15 [-3.40, 3.09]
    3 studies · 2594 participants
    GRADE not reported

Women who experienced preterm birth vs Women who did not experience preterm birth (term)

Dental caries · pregnant women

Women who experienced preterm birth did not have significantly higher DMFT than those who did not (mean difference 1.56, 95% CI -0.28 to 3.41; 5 studies; I2=92%); certainty of evidence not graded.

1 finding from 1 review
  • Dental caries and preterm birth: a systematic review and meta-analysis. 2018 All outcomes
    Pregnant women assessed around delivery in observational studies across multiple countries (Mexico, Malawi, India, France, Jordan, Finland, Tanzania); mostly retrospective cohort and case-control designs
    MD 1.56 [-0.28, 3.41]
    5 studies · 2963 participants
    GRADE not reported

Preterm birth (PTB) group vs Term birth (TB) group

Oral microbiome alpha diversity (Shannon index) · Pregnant women

In saliva samples Shannon diversity did not differ between preterm and term birth.

1 finding from 1 review

Preterm birth (PTB) group vs Term birth (TB) group

Oral microbiome alpha diversity (Shannon index) · Pregnant women

In V3-V4 studies Shannon diversity did not differ significantly, with very high heterogeneity.

1 finding from 1 review

Preterm birth (PTB) group vs Term birth (TB) group

Oral microbiome alpha diversity (Shannon index) · Pregnant women

In subgingival plaque Shannon diversity did not differ significantly, with very high heterogeneity.

1 finding from 1 review

Preterm birth (PTB) group vs Term birth (TB) group

Oral microbiome alpha diversity (Shannon index) · Pregnant women

Sensitivity analysis with Wan conversion gave a similar non-significant difference.

1 finding from 1 review

Preterm birth (PTB) group vs Term birth (TB) group

Oral microbiome alpha diversity (Shannon index) · Pregnant women

In Asian studies Shannon diversity did not differ significantly between preterm and term birth.

1 finding from 1 review

Preterm birth (PTB) group vs Term birth (TB) group

Oral microbiome alpha diversity (Shannon index) · Pregnant women

Sensitivity analysis with Hozo conversion gave a similar non-significant difference.

1 finding from 1 review

Preterm birth (<37 weeks gestation) vs Full-term birth (37 weeks or more gestation)

Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)

In children aged 3 years or younger, preterm birth was not associated with early childhood caries (OR 0.90, 95% CI 0.59 to 1.37); certainty not graded.

2 findings from 1 review

Preterm birth (oral health / enamel defects) vs Full-term children

Caries (DMFT) and enamel defects · Preterm children (about 8 years old) in the United Arab Emirates (Dubai)

One study found preterm children had higher DMFT and a fourfold higher prevalence of enamel defects than full-term children (narrative synthesis; not GRADE-rated).

1 finding from 1 review