Non-Cochrane · aetiology · PM32729621

Relationship between preterm, low birth weight and early childhood caries: a meta-analysis of the case-control and cross-sectional study.

Shi Linan, Jia Jinhai, Li Chunnian, et al. · Bioscience reports · 2020 · PubMed · doi:10.1042/bsr20200870

Oral HealthDental cariesAMSTAR 2: not applicable
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
5
current version
GRADE rated
0
No studies
0
Included studies
28
linked below
No studies 0 · 0%Ungraded 5 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationChildren aged 6 years or younger (preschool children)22 studies of children aged 6 years or younger (n=25,166 participants)
InterventionPreterm birth and/or low birth weight (<2500 g) as exposure factorsPreterm (16 studies; 21,279 participants) and low birth weight (15 studies)
ComparisonFull-term birth / normal birth weightFull-term birth / normal birth weight
OutcomesEarly childhood caries (ECC), expressed as odds ratio (OR) or adjusted OR with 95% CIEarly childhood caries (ECC)
Study designsEpidemiological studies (case-control and cross-sectional)22 studies: 7 case-control and 15 cross-sectional (15 cross-sectional and 2 case-control high quality; remaining case-control studies moderate quality)
TimingNot specifiedNot specified

Search date: Up to December 2019. Databases: PubMed; Wiley; Cochrane Library; Science Direct; China National Knowledge Infrastructure (CNKI); VIP Database for Chinese Technical Periodicals (VIP); Wanfang

Questions and results

Preterm birth (<37 weeks gestation) vs Full-term birth (37 weeks or more gestation)

Population: Children aged 6 years or younger (preschool children)
2 questions
OutcomeEffectEvidenceStatus / GRADE
Early childhood caries (ECC)
Children aged 3 years or younger
In children aged 3 years or younger, preterm birth was not associated with early childhood caries (OR 0.90, 95% CI 0.59 to 1.37); certainty not graded.
Source: Results 'Meta-analysis results'; Figure 4A (forest plot) · same question in other reviews
OR 0.90 [0.59, 1.37]2 studiesUngraded
Early childhood caries (ECC)
Overall
Preterm birth was associated with a significantly increased risk of early childhood caries (OR 1.59, 95% CI 1.36 to 1.87); certainty not graded.
Source: Abstract; Results 'Meta-analysis results'; Figure 2 (forest plot) · same question in other reviews
OR 1.59 [1.36, 1.87]16 studies · 21279 participantsUngraded

Low birth weight (<2500 g) vs Normal birth weight (2500 g or more)

Population: Children aged 6 years or younger (preschool children)
3 questions
OutcomeEffectEvidenceStatus / GRADE
Early childhood caries (ECC)
Adjusted OR
Adjusted analyses also showed no association between low birth weight and early childhood caries (adjusted OR 1.05, 95% CI 0.71 to 1.57); certainty not graded.
Source: Results 'Meta-analysis results'; Figure 3B (forest plot) · same question in other reviews
OR 1.05 [0.71, 1.57]2 studiesUngraded
Early childhood caries (ECC)
Children aged 3 years or younger
In children aged 3 years or younger, low birth weight was not associated with early childhood caries (OR 0.78, 95% CI 0.24 to 2.51); certainty not graded.
Source: Results 'Meta-analysis results'; Figure 4B (forest plot) · same question in other reviews
OR 0.78 [0.24, 2.51]3 studiesUngraded
Early childhood caries (ECC)
Overall (crude OR)
Low birth weight was not associated with early childhood caries (crude OR 1.12, 95% CI 0.94 to 1.33); certainty not graded.
Source: Abstract; Results 'Meta-analysis results'; Figure 3A (forest plot) · same question in other reviews
OR 1.12 [0.94, 1.33]15 studiesUngraded

Included primary studies 28

Open as a trial list
StudyAlso included byOutcomes it informs hereTrial PICOResults
Gopal 2016
matched by author and year (probable)
2 other reviewsnot statednot extracted yetnot extracted yet
Prakash 2012
matched by author and year (probable)
2 other reviewsnot statednot extracted yetnot extracted yet
Sridevi 2018
Factors associated with early childhood caries among 3 to 6 year old children in India: A case control study
DOI:10.3233/npm-181723
2 other reviewsnot statednot extracted yetnot extracted yet
Zhou 2011
Risk indicators for early childhood caries in 2‐year‐old children in southern China
DOI:10.1111/j.1834-7819.2010.01280.x
2 other reviewsnot statednot extracted yetnot extracted yet
Saravia 2007
Are intrauterine growth restriction and preterm birth associated with dental caries?
DOI:10.1111/j.1600-0528.2006.00345.x
1 other reviewnot statednot extracted yetnot extracted yet
Schuler 2017
Dental Caries and Developmental Defects of Enamel in the Primary Dentition of Preterm Infants: Case-Control Observational Study
DOI:10.1159/000480124
1 other reviewnot statednot extracted yetnot extracted yet
Campus 2008
National Pathfinder Survey on Children’s Oral Health in Italy: Pattern and Severity of Caries Disease in 4-Year-Olds
DOI:10.1159/000211719
this review onlynot statednot extracted yetnot extracted yet
Campus 2008
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Chen 2015
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Correa-Faria 2013
Factors associated with the development of early childhood caries among Brazilian preschoolers
DOI:10.1590/s1806-83242013005000021
this review onlynot statednot extracted yetnot extracted yet
Correa-Faria 2013
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Gopal 2016
DOI:10.3290/j.ohpd.a35619
this review onlynot statednot extracted yetnot extracted yet
Li 1996
Caries Experience in Deciduous Dentition of Rural Chinese Children 3–5 Years Old in Relation to the Presence or Absence of Enamel Hypoplasia
DOI:10.1159/000262130
this review onlynot statednot extracted yetnot extracted yet
Masumo 2014
Impact of low birthweight on early childhood caries in 6–36 months old infants in Uganda: A cross-sectional study
DOI:10.3109/00016357.2014.880189
this review onlynot statednot extracted yetnot extracted yet
Masumo 2014
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Miao 2011
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Miao 2015
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Olatosi 2014
The prevalence of early childhood caries and its associated risk factors among preschool children referred to a tertiary care institution
DOI:10.4103/1119-3077.156887
this review onlynot statednot extracted yetnot extracted yet
Olatosi 2014
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Rajshekar 2011
Comparison of primary dentition caries experience in pre-term low birth-weight and full-term normal birth-weight children aged one to six…
DOI:10.4103/0970-4388.84685
this review onlynot statednot extracted yetnot extracted yet
Rajshekar 2011
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Saravia 2007
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Schuler 2017
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Sridevi 2018
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Yang 2014
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Zhao 2010
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Zhen 2016
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet
Zhou 2011
matched by author and year (probable)
this review onlynot statednot extracted yetnot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match).