Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

140 questions · 147 findings · 26 reviews · Emergency and Critical Care

No studies found 24 · 16.3%GRADE not reported 2 · 1.4%Very low 56 · 38.1%Low 43 · 29.3%Moderate 12 · 8.2%High 10 · 6.8%

HALOPERIDOL vs placebo

The event rate of intensive care delirium within 28 days. · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

Haloperidol showed no clear difference in the event rate of intensive care delirium within 28 days. compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Stress intensity in the medical team members VAS (0 to 100; 0 = no stress; 100 = maximum stress)Â · relatives, patients, and healthcare professionals during resucitation
1 finding from 1 review

Summary of findings for the main comparison: cough augmentation techniques vs no cough augmentation technique

Adverse events 1. Hypotensionc 2. Hypertensiond 3. Secretion encumbrance resulting in severe hypoxaemia requiring reintubationc · critically‐ill mechanically‐ventilated adults and children requiring extubation from mechanical ventilation

It is very uncertain whether summary of findings for the main comparison: cough augmentation… changes adverse events 1. Hypotensionc 2. Hypertensiond 3. Secretion… compared with no cough augmentation technique (very low certainty).

1 finding from 1 review