All cause mortality · Patients with severe malaria
Pre‐referral rectal artesunate probably leads to lower all cause mortality compared with placebo (moderate certainty).
1 finding from 1 review
Neurodisability · Patients with severe malaria
Pre‐referral rectal artesunate showed no clear difference in neurodisability compared with placebo (low certainty).
1 finding from 1 review
Pre‐treatment loss to · people being investigated for tuberculosis (TB)
Impact of Xpert MTB/RIF probably leads to lower pre‐treatment loss to compared with smear microscopy (moderate certainty).
1 finding from 1 review
Clinical malaria episodes during pregnancy · HIV‐uninfected pregnant women
Mefloquine showed no clear difference in clinical malaria episodes during pregnancy compared with sulfadoxine‐pyrimethamine (high certainty).
1 finding from 1 review
Clinical malaria episodes during pregnancy · HIV‐infected pregnant women
Mefloquine plus cotrimoxazole showed no clear difference in clinical malaria episodes during pregnancy compared with cotrimoxazole (high certainty).
1 finding from 1 review
IRR 0.76 [0.33, 1.76]
1 study · 1 participants
High
Intervention not reported
Preterm birth · Pregnant women (parity 0‐1)
The intervention showed no clear difference in preterm birth (low certainty).
1 finding from 1 review
Intervention not reported
Preterm birth · Pregnant women (parity 2+)
1 finding from 1 review
Intervention not reported
Preterm birth · Pregnant women (all parities)
The intervention showed no clear difference in preterm birth (low certainty).
1 finding from 1 review
Intervention not reported
Preterm birth · Pregnant women (parity 0‐1)
The intervention showed no clear difference in preterm birth (low certainty).
1 finding from 1 review
Parasitaemia prevalence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)
MDA showed no clear difference in parasitaemia prevalence compared with no MDA (low certainty).
1 finding from 1 review
Parasitaemia prevalence · People of all ages living in an area with very low to low endemicity of P falciparum malaria ( < 10% prevalence)
It is very uncertain whether MDA changes parasitaemia prevalence compared with no MDA (very low certainty).
6 findings from 1 review
Show 3 more findings
Parasitaemia prevalence · People of all ages living in an area with very low to low endemicity of P vivax malaria (< 10% prevalence)
MDA may leads to lower parasitaemia prevalence compared with no MDA (low certainty).
6 findings from 1 review
Show 3 more findings
Intervention not reported
Preterm delivery · HIV‐positive women during pregnancy and immediate postpartum period
It is very uncertain whether the intervention changes preterm delivery (very low certainty).
1 finding from 1 review
Prevalence of DENV infection (any severity, any phenotype)a · children and adults at risk of dengue infection
wMel‐Wolbachia infected Aedes aegypti deployments probably leads to lower prevalence of DENV infection (any severity, any phenotype)a compared with no deployments (moderate certainty).
1 finding from 1 review
OR 0.23 [0.15, 0.35]
6306 participants
Moderate
Prevalence of dengue RNA in the mosquito population · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mosquito density (for population suppression strategy) · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Prevalence of Wolbachia‐carrying mosquitoes (for population replacement strategy) · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Diarrhoea prevalence (Children < 5a) · adults and children
The intervention probably leads to lower diarrhoea prevalence (Children < 5a) (moderate certainty).
1 finding from 1 review
Intervention not reported
Diarrhoea prevalence (All ages) · adults and children
The intervention may leads to lower diarrhoea prevalence (All ages) (low certainty).
1 finding from 1 review
Intervention not reported
Diarrhoea prevalence (Children < 5) · adults and children
The intervention may leads to lower diarrhoea prevalence (Children < 5) (low certainty).
1 finding from 1 review