Cochrane · systematic review · CD009964
Pre‐referral rectal artesunate for severe malaria
Okebe, J, Eisenhut, M · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pre‐referral rectal artesunate compared to placebo for severe malaria
Population: Children and adults with severe malaria
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All cause mortality Pre‐referral rectal artesunate vs placebo | RR 0.74 [0.59, 0.93] | 1 study · 8050 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Neurodisability Pre‐referral rectal artesunate vs placebo | RR 0.68 [0.35, 1.3] | 1 study · 17280 participants | Low Downgraded: risk of bias, imprecision |