Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

897 questions · 966 findings · 73 reviews

No studies found 269 · 27.8%GRADE not reported 101 · 10.5%Very low 284 · 29.4%Low 180 · 18.6%Moderate 107 · 11.1%High 25 · 2.6%

Pharmacological treatment vs pharmacological treatment 2

All‐cause mortality ‐ short term (end of treatment) · health problem or population

It is very uncertain whether summary of findings table ‐ Pharmacological treatment 1 changes all‐cause mortality ‐ short term (end of treatment) compared with pharmacological treatment 2 (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).

4 findings from 1 review
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Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus clonidine plus amantadine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus buprenorphine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus buprenorphine, inpatient… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: methadone versus methadone plus gabapentin · management of opium withdrawal

Pharmacological detoxification treatment showed no clear difference in completion of treatment: methadone versus methadone plus gabapentin compared with other pharmacological detoxification treatment (low certainty).

1 finding from 1 review