Pharmacological detoxification treatment vs other pharmacological detoxification treatment: Completion of treatment
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pharmacological detoxification treatment vs other pharmacological detoxification treatment Completion of treatment: baclofen versus clonidine · management of opium withdrawal It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty). Pharmacological therapies for management of opium withdrawal (2018) · Cochrane Headline outcomes only | RR 1.06 [0.63, 1.8] | 66 participants | Very low |
Pharmacological detoxification treatment vs other pharmacological detoxification treatment Completion of treatment: clonidine versus methadone · management of opium withdrawal Pharmacological detoxification treatment may leads to higher completion of treatment: clonidine versus methadone compared with other pharmacological detoxification treatment (low certainty). Pharmacological therapies for management of opium withdrawal (2018) · Cochrane Headline outcomes only | RR 2.01 [1.69, 2.38] | 361 participants | Low |
Pharmacological detoxification treatment vs other pharmacological detoxification treatment Completion of treatment: methadone versus tramadol · management of opium withdrawal It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: methadone versus tramadol compared with other pharmacological detoxification treatment (very low certainty). Pharmacological therapies for management of opium withdrawal (2018) · Cochrane Headline outcomes only | RR 0.95 [0.65, 1.37] | 72 participants | Very low |
Pharmacological detoxification treatment vs other pharmacological detoxification treatment Completion of treatment: tincture of opium versus methadone · management of opium withdrawal Pharmacological detoxification treatment showed no clear difference in completion of treatment: tincture of opium versus methadone compared with other pharmacological detoxification treatment (low certainty). Pharmacological therapies for management of opium withdrawal (2018) · Cochrane Headline outcomes only | RR 1 [0.95, 1.05] | 1 study · 74 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.