Cochrane · systematic review · CD013217
Non‐pharmacological care for opioid withdrawal in newborns
Pahl, A, Young, L, Buus-Frank, ME, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
2
No studies
3
Included studies
NR
No studies 3 · 60%Ungraded 0 · 0%Very low 2 · 40%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Non‐pharmacological treatment compared to placebo for infants at risk for, or having early symptoms consistent with, opioid withdrawal
Population: infants at risk for, or having early symptoms consistent with, opioid withdrawal
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Primary outcome measures Non‐pharmacological treatment vs placebo | no estimate extracted | NR | No studies |
– Modifying environmental stimulation Non‐pharmacological treatment vs placebo | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision |
– Feeding practices Non‐pharmacological treatment vs placebo | no estimate extracted | NR | No studies |
– Support of the mother‐infant dyad Non‐pharmacological treatment vs placebo | no estimate extracted | 1 study · 14 participants | Very low Downgraded: risk of bias, imprecision |
NICU admission Non‐pharmacological treatment vs placebo | no estimate extracted | NR | No studies |