Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Postoperative opioid consumption, 'overall' (MEQ, mg) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Gastrointestinal recovery · adults undergoing surgery with general anaesthesia
It is very uncertain whether intravenous (IV) lidocaine changes gastrointestinal recovery compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Nausea · adults undergoing surgery with general anaesthesia
It is very uncertain whether intravenous (IV) lidocaine changes postoperative nausea, 'overall' (0 to 24 h, to 48 h, to 72 h) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Postoperative opioid consumption, 'overall' (MEQ, mg) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Gastrointestinal recovery · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Nausea · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · participants undergoing surgery with peripheral nerve block
3 findings from 1 review
no estimate extracted
3 studies · 172 participants
Low
no estimate extracted
3 studies · 162 participants
Low
no estimate extracted
5 studies · 257 participants
Low
Duration of sensory block (we included all studies describing duration of sensory block regardless of how it was described) · participants undergoing surgery with peripheral nerve block
1 finding from 1 review
Incidence of serious adverse events (we used the NIH definition of adverse events. A serious event includes death, a life‐threatening event that requires hospitalization or prolonged hospitalization, disability or congenital anomaly) · participants undergoing surgery with peripheral nerve block
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Anaesthetic agent (Intravenous used) mcg/kg/min7 · adults and children undergoing general anaesthesia
1 finding from 1 review
Intervention not reported
Amount of 'rescue' opioid (intravenous morphine equivalents, mg) · adults having abdominal surgery
1 finding from 1 review
Mortality (in‐hospital death and 30‐day mortality) · adults receiving intravenous fluids whilst undergoing any form of surgery
Buffered showed no clear difference in mortality (in‐hospital death and 30‐day mortality) compared with non‐buffered crystalloid intravenous fluid (low certainty).
1 finding from 1 review
Organ system failure ‐ renal insufficiency requiring support · adults receiving intravenous fluids whilst undergoing any form of surgery
Buffered showed no clear difference in organ system failure ‐ renal insufficiency requiring support compared with non‐buffered crystalloid intravenous fluid (low certainty).
1 finding from 1 review
Plasma pH ‐ postoperative pH · adults receiving intravenous fluids whilst undergoing any form of surgery
1 finding from 1 review
Postoperative chloride mmol/L · adults receiving intravenous fluids whilst undergoing any form of surgery
1 finding from 1 review
Joint pain at rest · adults having abdominal surgery
1 finding from 1 review