Cochrane · systematic review · CD004089
Perioperative administration of buffered versus non‐buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures
Bampoe, S, Odor, PM, Dushianthan, A, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsBuffered versus non‐buffered crystalloid intravenous fluid for adults undergoing any form of surgery
Population: adults receiving intravenous fluids whilst undergoing any form of surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (in‐hospital death and 30‐day mortality) Buffered vs non‐buffered crystalloid intravenous fluid | OR 1.85 [0.37, 9.33] | 3 studies · 267 participants | Low Downgraded: risk of bias, imprecision |
Organ system failure ‐ renal insufficiency requiring support Buffered vs non‐buffered crystalloid intravenous fluid | OR 0.82 [0.34, 1.98] | 4 studies · 267 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Plasma pH ‐ postoperative pH Buffered vs non‐buffered crystalloid intravenous fluid | no estimate extracted | 12 studies · 720 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Serum chloride (mmol/L) ‐ postoperative chloride Buffered vs non‐buffered crystalloid intravenous fluid | no estimate extracted | 10 studies · 530 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |