Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

41 questions · 49 findings · 18 reviews

No studies found 9 · 18.4%GRADE not reported 9 · 18.4%Very low 13 · 26.5%Low 10 · 20.4%Moderate 8 · 16.3%High 0 · 0%

Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)

Proportion of people whose symptoms 'improved' (short term: 4 to 12 weeks) · symptomatic gastroparesis

It is very uncertain whether acupuncture plus routine care/diabetes control changes proportion of people whose symptoms 'improved' (short term: 4 to 12… compared with the same treatment alone (routine care/diabetes control) (very low certainty).

1 finding from 1 review

VIDEO GAMES (COMMERCIAL NON‐EXERGAMES) (plus standard care) vs COGNITIVE REMEDIATION (plus standard care)

Cognitive function · patients with schizophrenia

VIDEO GAMES (COMMERCIAL NON‐EXERGAMES) (plus standard care) may leads to lower functioning: specific ‐ cognitive ‐ improved (MCCB, at least 1… compared with COGNITIVE REMEDIATION (plus standard care) (low certainty).

1 finding from 1 review

Technology‐mediated psychoeducation + standard care intervention vs usual care

Global state: not improved ‐ short‐term GAF · schizophrenia

Technology‐mediated psychoeducation + standard care intervention showed no clear difference in global state: not improved ‐ short‐term GAF compared with standard care intervention (low certainty).

1 finding from 1 review

Technology‐mediated psychoeducation + standard care intervention vs usual care

Knowledge/insight: not improved ITAQ · schizophrenia

Technology‐mediated psychoeducation + standard care intervention showed no clear difference in knowledge/insight: not improved ITAQ compared with standard care intervention (low certainty).

1 finding from 1 review

Technology‐mediated psychoeducation + standard care intervention vs usual care

Clinical response: no clinically significant response in mental state · schizophrenia

Technology‐mediated psychoeducation + standard care intervention showed no clear difference in mental state: not improved ‐ short‐term BPRS compared with standard care intervention (low certainty).

1 finding from 1 review

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - improvement ('healed' or 'improved' vs… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.

5 findings from 1 review
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Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.

5 findings from 1 review
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Yoga vs NON‐STANDARD CARE

Mental state‐ general Not improved to an important extent · patients with schizophrenia

YOGA showed no clear difference in mental state: clinically important change PANSS ‐ not improved compared with NON‐STANDARD CARE (low certainty).

1 finding from 1 review

Yoga vs NON‐STANDARD CARE

Social functioning: clinically important change SOFS ‐ overall, not improved · patients with schizophrenia

YOGA showed no clear difference in social functioning: clinically important change SOFS ‐ overall, not… compared with NON‐STANDARD CARE (low certainty).

1 finding from 1 review

Yoga vs usual care

Global state: no improvement ‐ medium termAs defined in each study · patients with schizophrenia

YOGA probably leads to lower mental state: Overall ‐ not improved PANSS compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

Yoga vs usual care

Social functioning · patients with schizophrenia

YOGA showed no clear difference in social functioning: Overall ‐ not improved SOFS compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

Inactivated-bacteria tablets vs Placebo, fluoride toothpaste, or standard post-filling care (varies by trial)

Improved caries prognosis via restored oral microbiota · Patients after dental filling

Adjuvant postbiotics after dental filling improve caries prognosis by restoring the oral microbiota in one RCT (ungraded).

1 finding from 1 review
  • Postbiotics and Dental Caries: A Systematic Review. 2025 All outcomes
    14 days · Clinical; salivary/plaque sampling
    One RCT reported that adjuvant postbiotic tablets after dental filling improved caries prognosis by restoring oral microbiota diversity, structure and function and reducing potentially pathogenic bacteria (Liu 2024);…
    1 study
    GRADE not reported