Question · asked by 1 review
Inactivated-bacteria tablets vs Placebo, fluoride toothpaste, or standard post-filling care (varies by trial): Improved caries prognosis via restored oral microbiota
- Population
- Patients after dental filling
- Intervention
- Inactivated-bacteria tablets
- Comparison
- Placebo, fluoride toothpaste, or standard post-filling care (varies by trial)
- Outcome
- Improved caries prognosis via restored oral microbiota
Adjuvant postbiotics after dental filling improve caries prognosis by restoring the oral microbiota in one RCT (ungraded).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Inactivated-bacteria tablets (Probio-Eco) vs Placebo, fluoride toothpaste, or standard post-filling care (varies by trial) Improved caries prognosis via restored oral microbiota · Patients after dental filling · 14 days, Clinical; salivary/plaque sampling Adjuvant postbiotics after dental filling improve caries prognosis by restoring the oral microbiota in one RCT (ungraded). Postbiotics and Dental Caries: A Systematic Review. (2025) All outcomes | One RCT reported that adjuvant postbiotic tablets after dental filling improved caries prognosis by restoring oral microbiota diversity, structure and function and reducing potentially pathogenic bacteria (Liu 2024);… | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Postbiotics and Dental Caries: A Systematic Review. 2025 All outcomes | October 2024 | 21 | Critically Low / Critically Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.