Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy · adult parapneumonic effusions and empyema
It is very uncertain whether fibrinolytics changes overall treatment failure, including mortality, thoracic surgery or… compared with placebo (very low certainty).
1 finding from 1 review
Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · patients with chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Quinolone showed no clear difference in number of participants experiencing one or more exacerbations… compared with tetracycline (low certainty).
1 finding from 1 review
Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · patients with chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Quinolone showed no clear difference in number of participants experiencing one or more exacerbations… compared with macrolide (low certainty).
1 finding from 1 review
Mortality. · adult parapneumonic effusions and empyema
Fibrinolytics showed no clear difference in mortality. compared with placebo (moderate certainty).
1 finding from 1 review
Referral for thoracic surgery (open or thorascopic) · adult parapneumonic effusions and empyema
Fibrinolytics may leads to lower referral for thoracic surgery. compared with placebo (low certainty).
1 finding from 1 review
Serious adverse events · adult parapneumonic effusions and empyema
Fibrinolytics showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
PEF (L/min) · patients with adults with acute asthma
Aminophylline showed no clear difference in PEF (L/min) ‐ at 60 min compared with placebo (low certainty).
1 finding from 1 review
Hospital admissions · patients with adults with acute asthma
Aminophylline showed no clear difference in hospital admissions compared with placebo (moderate certainty).
1 finding from 1 review
Tremor · patients with adults with acute asthma
Aminophylline showed no clear difference in tremor compared with placebo (low certainty).
1 finding from 1 review
Vomiting · patients with adults with acute asthma
Aminophylline probably leads to higher vomiting compared with placebo (moderate certainty).
1 finding from 1 review
Arrhythmia/palpitations · patients with adults with acute asthma
Aminophylline probably leads to higher arrhythmia/palpitations compared with placebo (moderate certainty).
1 finding from 1 review
Convulsions · patients with adults with acute asthma
1 finding from 1 review
Response rate ‐ P aeruginosa eradication · adults with bronchiectasis
It is very uncertain whether polymyxins changes response rate ‐ P aeruginosa eradication compared with aminoglycosides (very low certainty).
1 finding from 1 review
All‐cause mortality · patients with chronic obstructive pulmonary disease
1 finding from 1 review
All‐cause mortality · patients with chronic obstructive pulmonary disease
1 finding from 1 review
Exacerbations · people with asthma
Tailored interventions based on sputum eosinophils probably leads to lower number of participants who had one or more exacerbations over the… compared with tailored interventions based on clinical symptoms (moderate certainty).
1 finding from 1 review
Hospital admissions · people with asthma
Tailored interventions based on sputum eosinophils probably leads to lower hospitalisations compared with tailored interventions based on clinical symptoms (moderate certainty).
1 finding from 1 review
Mean dose of inhaled corticosteroids per person per day (BUD equivalent mcg/day) · people with asthma
1 finding from 1 review