Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

56 questions · 69 findings · 13 reviews · Oral Health

No studies found 13 · 18.8%GRADE not reported 32 · 46.4%Very low 14 · 20.3%Low 6 · 8.7%Moderate 4 · 5.8%High 0 · 0%

Higher BMI (continuous / per-unit increment) vs Lower BMI (continuous reference / per 1 kg/m2 decrement)

Dental caries in children · Children (approx. 4-18 years)

Pooling studies that used BMI as a continuous variable showed no significant association between per-unit BMI and childhood dental caries (OR 1.01, 95% CI 0.99 to 1.03; I2=3.5%); ungraded.

3 findings from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Patient-reported altered sensation (spontaneous or evoked: anaesthesia/paraesthesia/dysaesthesia/hyperalgesia/allodynia) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

It is very uncertain whether low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… changes patient-reported altered sensation (spontaneous or evoked:… compared with placebo (sham) laser therapy (very low certainty).

2 findings from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Somatosensory evoked potentials · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Mechanosensory perception (load in grams to elicit sensation; Semmes Weinstein monofilaments) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

Low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… led to higher mechanosensory perception (load in grams to elicit sensation; Semmes… compared with placebo (sham) laser therapy; GRADE not reported.

1 finding from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Thermosensory (thermal) perception · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

Low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… showed no clear difference in thermosensory (thermal) perception compared with placebo (sham) laser therapy; GRADE not reported.

1 finding from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Patient satisfaction · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Overweight vs Normal Weight or Non‐Obese

Caries experience (mean DMFT) · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)

Overweight may make little or no difference to caries experience (dmft) in the primary dentition of Brazilian children (very low certainty).

1 finding from 1 review

Overweight vs Normal Weight or Non‐Obese

Caries experience (mean DMFT) · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)

Overweight may make little or no difference to caries experience (DMFT) in the permanent dentition (very low certainty).

1 finding from 1 review

Obesity (Unclassified) vs Normal Weight or Non‐Obese

Caries experience (mean DMFT) · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)

Obesity may make little or no difference to caries experience (dmft) in the primary dentition (very low certainty).

1 finding from 1 review

Obesity (Unclassified) vs Normal Weight or Non‐Obese

Caries experience (mean DMFT) · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)

Normal-weight adolescents may have higher caries experience (DMFT) than obese peers in the permanent dentition, but the evidence is very uncertain (very low certainty).

1 finding from 1 review

Malocclusion vs No malocclusion

Oral health-related quality of life · Indian children, adolescents and adults

One GOHAI study found no significant difference in OHRQoL by malocclusion status; ungraded.

2 findings from 1 review

Bruxism vs No bruxism

Oral health-related quality of life · Indian children and adults

Two studies found bruxers have poorer OHRQoL than non-bruxers; narrative, ungraded.

1 finding from 1 review