Completion of treatment · management of opium withdrawal
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).
2 findings from 1 review
RR 1.06 [0.63, 1.8]
66 participants
Very low
RR 2.01 [1.69, 2.38]
361 participants
Low
Completion of treatment: clonidine versus clonidine plus amantadine, inpatient setting · management of opium withdrawal
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).
1 finding from 1 review
RR 1.03 [0.86, 1.24]
69 participants
Very low
Completion of treatment: clonidine versus buprenorphine, inpatient setting · management of opium withdrawal
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus buprenorphine, inpatient… compared with other pharmacological detoxification treatment (very low certainty).
1 finding from 1 review
RR 1.04 [0.9, 1.2]
35 participants
Very low
Withdrawal symptoms · management of opium withdrawal
2 findings from 1 review
no estimate extracted
60 participants
Very low
no estimate extracted
34 participants
Very low
Intervention not reported
Number commencing naltrexone maintenance treatment ‐ Clonidine comparison · patients with opioid withdrawal
The intervention probably leads to higher number commencing naltrexone maintenance treatment ‐ Clonidine… (moderate certainty).
1 finding from 1 review
Intervention not reported
Retained in naltrexone maintenance treatment or abstinent at 12 weeks ‐ Clonidine comparison · patients with opioid withdrawal
The intervention probably leads to higher retained in naltrexone maintenance treatment or abstinent at 12… (moderate certainty).
1 finding from 1 review
Drop‐out (end of treatment) · patients with opiate dependent adolescents
Buprenorphine showed no clear difference in drop out Number of participants who did not complete the… compared with clonidine (moderate certainty).
1 finding from 1 review
Withdrawal symptoms · patients with opiate dependent adolescents
1 finding from 1 review
Initiation of naltrexone treatment Number of participants initiating naltrexone · patients with opiate dependent adolescents
Buprenorphine probably leads to higher initiation of naltrexone treatment Number of participants initiating… compared with clonidine (moderate certainty).
1 finding from 1 review