Number requiring additional analgesia at any time postoperatively ‐ low dose clonidine · patients with postoperative pain
Clonidine showed no clear difference in number requiring additional analgesia at any time postoperatively ‐… compared with placebo or no treatment (low certainty).
1 finding from 1 review
Number requiring additional analgesia at any time postoperatively ‐ high dose clonidine · patients with postoperative pain
Clonidine probably leads to lower number requiring additional analgesia at any time postoperatively ‐… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Number requiring additional analgesia at any time postoperatively ‐ high dose clonidine, studies with lower risk of bias · patients with postoperative pain
Clonidine probably leads to lower number requiring additional analgesia at any time postoperatively ‐… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Postoperative pain score ‐ low dose clonidine · patients with postoperative pain
1 finding from 1 review
Postoperative pain score ‐ high dose clonidine · patients with postoperative pain
1 finding from 1 review
Number requiring additional analgesia at any time postoperatively ‐ low dose clonidine · patients with postoperative pain
Clonidine may leads to lower number requiring additional analgesia at any time postoperatively ‐… compared with midazolam (low certainty).
1 finding from 1 review
Number requiring additional analgesia at any time postoperatively ‐ high dose clonidine · patients with postoperative pain
Clonidine may leads to lower number requiring additional analgesia at any time postoperatively ‐… compared with midazolam (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · neonates with mechanical ventilation
Clonidine showed no clear difference in all‐cause mortality during initial hospitalization compared with placebo (low certainty).
1 finding from 1 review
aOne study and few events · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number requiring opioids postoperatively · patients with postoperative pain
Clonidine showed no clear difference in number requiring opioids postoperatively compared with fentanyl (moderate certainty).
1 finding from 1 review
Single small study · patients with postoperative pain
1 finding from 1 review
no estimate extracted
1 participants
GRADE not reported
Haemodynamic or respiratory changes requiring intervention · patients with postoperative pain
Clonidine probably leads to lower haemodynamic or respiratory changes requiring intervention compared with midazolam (moderate certainty).
1 finding from 1 review
Additional analgesia required (escape analgesia) · patients with postoperative pain
Clonidine showed no clear difference in number requiring additional analgesia at any time postoperatively compared with fentanyl (moderate certainty).
1 finding from 1 review
Additional analgesia required (escape analgesia) · patients with postoperative pain
High dose clonidine showed no clear difference in number requiring additional analgesia required postoperatively ‐ all… compared with low dose clonidine (low certainty).
1 finding from 1 review
Number requiring additional analgesia required postoperatively ‐ moderate quality studies · patients with postoperative pain
High dose clonidine may leads to lower number requiring additional analgesia required postoperatively ‐… compared with low dose clonidine (low certainty).
1 finding from 1 review
Postoperative pain score · patients with postoperative pain
1 finding from 1 review
ADHD symptom‐related behavior Measured by standardized rating scales: Conners' Abbreviated Teacher Rating Scale, Conners' Abbreviated Parent Rating Scale, IOWA Conners' Teacher Rating Scale, Conners' Continuous Performance Task, Child Behaviour Ch... · children with ADHD and comorbid tic disorders
1 finding from 1 review
Tic severity Measured by standardized rating scales: Yale Global Tic Severity Scale, Tourette Syndrome Severity Scale, Global Tic Rating Scale, Tic Symptom Self‐Report, Hopkins Motor/Vocal Scale · children with ADHD and comorbid tic disorders
1 finding from 1 review
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found