Cochrane · systematic review · CD012468
Clonidine for sedation and analgesia for neonates receiving mechanical ventilation
Romantsik, O, Calevo, MG, Norman, E, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
1
No studies
1
Included studies
NR
No studies 1 · 50%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Clonidine versus placebo for neonates receiving mechanical ventilation
Population: neonates receiving mechanical ventilation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality during initial hospitalization Clonidine vs placebo | RR 0.69 [0.12, 3.98] | 1 study · 112 participants | Low Downgraded: imprecision |
aOne study and few events Clonidine vs placebo | no estimate extracted | NR | No studies |