HIV-related oral lesions · Children and adolescents living with HIV on ART/HAART
Lower CD4+ counts (<250 cells/mm3) were associated with roughly twice the odds of HIV-related oral lesions in two studies (not pooled).
1 finding from 1 review
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review… 2022 All outcomesCross-sectional (case-control; single time point) · HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal) · CD4+ T-cell count <250 cells/mm3 vs higher
CLWH with CD4+ <250 cells/mm3 were about twice as likely to have HIV-related oral lesions: Baghirath 2013 OR 1.916 (95% CI 0.613 to 2.513), p=0.001; Divakar 2015 OR 1.999 (95% CI 0.129 to 3.688), p=0.001. Not pooled.
2 studies
GRADE not reported
HIV-related oral lesions · Children living with HIV receiving ART
One reported study did not show a clear difference in HIV-related oral lesions for children with CD4+ T-cell counts below 250 cells/mm3.
2 findings from 1 review
OR 1.916 [0.613, 2.513]
1 study
GRADE not reported
OR 1.999 [0.129, 3.688]
1 study
GRADE not reported
Periodontal disease and serum IL-1β IL-6 and cortisol · Patients with aggressive or chronic periodontitis at a university periodontology department
No correlation was reported between immunological markers cortisol and registered stress values; untreated aggressive periodontitis was accompanied by pessimistic attitude and elevated serum IL-6.
1 finding from 1 review
GCF elastase activity and non-surgical periodontal treatment outcome (salivary cortisol, ICTP measured; no effect reported) · Adults with periodontitis needing non-surgical periodontal treatment
In one 6-month longitudinal study, patients under psychosocial stress had higher gingival crevicular fluid elastase and poorer outcomes after non-surgical periodontal therapy; not pooled (ungraded).
1 finding from 1 review
Gingival inflammation and GCF IL-1β IL-6 and IL-8 · Adults with gingivitis or periodontitis from a private periodontics practice
Perceived stress was associated with IL-1β IL-6 and IL-8 levels in gingival crevicular fluid.
1 finding from 1 review
Periodontitis and GCF IL-6 · Women on long-term sick leave for depression
Depressed women had higher periodontal disease and GCF IL-6 after adjustment for age and smoking.
1 finding from 1 review
Periodontitis and allostatic load · US adults in NHANES III
Allostatic load partly explained socioeconomic gradients in periodontal disease.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Antibody titres to periodontal pathogens · Adults with periodontitis
In one case-control study, depression as a marker of social isolation was associated with elevated antibody titres to periodontal pathogens at baseline and 1-year follow-up; not pooled (ungraded).
1 finding from 1 review
Periodontitis and allostatic load · US adults in NHANES 1999-2004
Allostatic load increased the probability of periodontitis and the association varied by race/ethnicity.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Intervention not reported
Serum inflammatory cytokines (IL-1b, IL-6) and cortisol in periodontitis
1 finding from 1 review
Dental caries in children · Mother-child pairs
In one cross-sectional study, higher maternal allostatic load was associated with child dental caries experience and with health-related maternal care-taking behaviours; not pooled (ungraded).
1 finding from 1 review
Salivary cortisol, cariogenic bacterial load and dental caries · Kindergarten-age children
In one cross-sectional study of children, low socioeconomic status, higher basal salivary cortisol and higher cariogenic bacterial counts were each independently associated with higher dental caries risk; not pooled (ungraded).
1 finding from 1 review
Intervention not reported
Enamel surface properties (thinner, softer enamel) in exfoliated teeth
1 finding from 1 review
Systemic inflammation (C-reactive protein) and periodontal disease progression · General-population adults (German cohort)
In one 5-year longitudinal study, accumulation of low socioeconomic and behavioural factors was associated with greater periodontal disease progression and higher C-reactive protein; not pooled (ungraded).
1 finding from 1 review