Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

26 questions · 26 findings · 4 reviews

No studies found 0 · 0%GRADE not reported 5 · 19.2%Very low 9 · 34.6%Low 9 · 34.6%Moderate 3 · 11.5%High 0 · 0%

CBT plus standard care vs usual care

Global state: 2. Clinically important change (no improvement) ‐ long term · patients with schizophrenia

It is very uncertain whether COMPARISON 1: CBT+ STANDARD CARE changes global state: 2. Clinically important change (no improvement) ‐ long… compared with STANDARD CARE ALONE (very low certainty).

1 finding from 1 review

CBT plus standard care vs usual care

Mental state: General ‐ clinically important change (no improvement) · patients with schizophrenia

It is very uncertain whether COMPARISON 1: CBT+ STANDARD CARE changes mental state: General ‐ clinically important change (no improvement)… compared with STANDARD CARE ALONE (very low certainty).

1 finding from 1 review

CBT plus standard care vs usual care

Adverse events experienced at short or long term ‐ general adverse events 24 weeks' · patients with schizophrenia

It is very uncertain whether COMPARISON 1: CBT+ STANDARD CARE changes adverse events: General: any adverse event compared with STANDARD CARE ALONE (very low certainty).

1 finding from 1 review

CBT plus standard care vs usual care

Satisfaction with treatment: 1. Leaving the study early ‐ long term · patients with schizophrenia

COMPARISON 1: CBT+ STANDARD CARE showed no clear difference in satisfaction with treatment: 1. Leaving the study early ‐ long term compared with STANDARD CARE ALONE (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Cognitive behavioural therapy plus standard care vs control

Global state ‐ number of participants with relapse/exacerbations of psychosis (combined time points) · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)

Summary of findings table ‐ Cognitive behavioural therapy plus… showed no clear difference in global state ‐ number of participants with relapse/exacerbations of… compared with control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Cognitive behavioural therapy plus standard care vs control

Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points) · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)

Summary of findings table ‐ Cognitive behavioural therapy plus… showed no clear difference in leaving the study early ‐ for any reason ‐ overall acceptability… compared with control (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Cognitive behavioural therapy plus standard care vs control

Risk for at least one adverse event per patient · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)

It is very uncertain whether summary of findings table ‐ Cognitive behavioural therapy plus… changes adverse events ‐ participants with at least one adverse event ‐ < 12… compared with control (very low certainty).

1 finding from 1 review