Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

36 questions · 36 findings · 7 reviews

No studies found 3 · 8.3%GRADE not reported 5 · 13.9%Very low 5 · 13.9%Low 10 · 27.8%Moderate 10 · 27.8%High 3 · 8.3%

Buffered vs non‐buffered crystalloid intravenous fluid

Mortality (in‐hospital death and 30‐day mortality) · adults receiving intravenous fluids whilst undergoing any form of surgery

Buffered showed no clear difference in mortality (in‐hospital death and 30‐day mortality) compared with non‐buffered crystalloid intravenous fluid (low certainty).

1 finding from 1 review

Buffered vs non‐buffered crystalloid intravenous fluid

Organ system failure ‐ renal insufficiency requiring support · adults receiving intravenous fluids whilst undergoing any form of surgery

Buffered showed no clear difference in organ system failure ‐ renal insufficiency requiring support compared with non‐buffered crystalloid intravenous fluid (low certainty).

1 finding from 1 review

Buffered 'Prophylin' prophylactic gel vs Placebo gel

Oral health (oral pH, cariogenic bacteria, Candida) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review