Question · asked by 1 review
Buffered 'Prophylin' prophylactic gel vs Placebo gel: Oral health (oral pH, cariogenic bacteria, Candida)
- Population
- Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy, haemodialysis)
- Intervention
- Buffered 'Prophylin' prophylactic gel
- Comparison
- Placebo gel
- Outcome
- Oral health (oral pH, cariogenic bacteria, Candida)
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Buffered 'Prophylin' prophylactic gel vs Placebo (unbuffered gel / water) Oral health (oral pH, cariogenic bacteria, Candida) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's… Interventions for the management of dry mouth: topical therapies (2011) · Cochrane All outcomes | No difference between buffered gel, unbuffered gel and water for oral pH, cariogenic bacteria or Candida species. | 1 study · 14 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes | 2011-10 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.