Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 38 findings · 12 reviews · Pregnancy and Childbirth

No studies found 7 · 18.4%GRADE not reported 10 · 26.3%Very low 11 · 28.9%Low 3 · 7.9%Moderate 6 · 15.8%High 1 · 2.6%

Upright position vs recumbent position

Abnormal fetal heart rate patterns, requiring intervention · women in the second stage of labour with epidural anaesthesia

It is very uncertain whether upright position changes abnormal fetal heart rate patterns, requiring intervention compared with recumbent position (very low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline with continuation of oxytocic infusion vs cessation of oxytocic infusion without tocolytic agent

Abnormal FHR tracing · women who developed uterine hyperstimulation in labour with oxytocin augmentation, but without signs of fetal distress

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs no tocolytic agent, whilst awaiting emergency delivery

Abnormal FHR tracing · women in labour with signs of fetal distress and a fetal scalp pH < 7.25, for whom the decision had been made for emergency delivery

Summary of findings for subcutaneous terbutaline probably leads to lower abnormal FHR tracing compared with no tocolytic agent, whilst awaiting emergency delivery (moderate certainty).

1 finding from 1 review

Summary of findings for selective ß2‐adrenergic agonist vs no tocolytic agent, whilst awaiting emergency delivery

Abnormal FHR as defined by trial authors (FHR tracing not improved) · women with fetal distress for whom the decision had been made to delivery by emergency caesarean section

Summary of findings for selective ß2‐adrenergic agonist probably leads to lower abnormal FHR as defined by trial authors (FHR tracing not improved) compared with no tocolytic agent, whilst awaiting emergency delivery (moderate certainty).

1 finding from 1 review

Discontinued intravenous (IV) oxytocin stimulation vs continued IV oxytocin stimulation

Uterine tachysystole combined with abnormal fetal heart rate · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…

Discontinued intravenous (IV) oxytocin stimulation probably leads to lower uterine tachysystole combined with abnormal fetal heart rate compared with continued IV oxytocin stimulation (moderate certainty).

1 finding from 1 review

Discontinued intravenous (IV) oxytocin stimulation vs continued IV oxytocin stimulation

Intrapartum cardiotocography (CTG) abnormalities (suspicious/pathological CTGs) · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…

Discontinued intravenous (IV) oxytocin stimulation probably leads to lower intrapartum cardiotocography (CTG) abnormalities… compared with continued IV oxytocin stimulation (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo

Congenital abnormalities · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes congenital abnormalities compared with placebo (very low certainty).

1 finding from 1 review

Routine/revealed vs selective/concealed ultrasound

Detection of fetal abnormality before 24 weeks' gestation · Fetal ultrasound assessment before 24 weeks' gestation

Routine/revealed probably leads to higher detection of fetal abnormality before 24 weeks' gestation compared with selective/concealed ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Fetal heart rate abnormality in labour · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in fetal heart rate abnormality in labour compared with transvaginal ultrasound; GRADE not reported.

1 finding from 1 review

Intervention not reported

Caesarean section (all indications) Â · women with an abnormal CTG in labour

It is very uncertain whether the intervention changes caesarean section (all indications) Â (very low certainty).

1 finding from 1 review