Cochrane · systematic review · CD014698

Routine ultrasound for fetal assessment before 24 weeks' gestation

Kaelin Agten, A, Xia, J, Servante, JA, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 4 · 40%Very low 0 · 0%Low 2 · 20%Moderate 4 · 40%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

First trimester routine compared to selective ultrasound for fetal assessment before 24 weeks' gestation

Population: Fetal ultrasound assessment before 24 weeks' gestation
5 questions
OutcomeEffectEvidenceStatus / GRADE
Maternal anxiety3
First trimester routine vs selective ultrasound
RR 0.8 [0.65, 0.99]1 study · 634 participantsModerate
Downgraded: risk of bias
Perinatal loss
First trimester routine vs selective ultrasound
RR 0.97 [0.55, 1.73]1 study · 648 participantsLow
Downgraded: risk of bias
Induction of labour for post‐maturity
First trimester routine vs selective ultrasound
RR 0.83 [0.5, 1.37]3 studies · 1474 participantsLow
Downgraded: risk of bias
Termination for major abnormality
First trimester routine vs selective ultrasound
no estimate extracted0 studies · 0 participantsUngraded
Birth before 34 weeks' gestation
First trimester routine vs selective ultrasound
no estimate extracted0 studies · 0 participantsUngraded

Second trimester routine versus selective ultrasound for fetal assessment before 24 weeks' gestation

Population: Fetal ultrasound assessment before 24 weeks' gestation
5 questions
OutcomeEffectEvidenceStatus / GRADE
Perinatal loss
Second trimester routine vs selective ultrasound
RR 0.98 [0.81, 1.2]3 studies · 17918 participantsModerate
Induction of labour for post‐maturity
Second trimester routine vs selective ultrasound
RR 0.48 [0.31, 0.73]6 studies · 24174 participantsModerate
Downgraded: risk of bias, inconsistency
Termination of pregnancy for fetal abnormality
Second trimester routine vs selective ultrasound
RR 2.36 [1.13, 4.93]4 studies · 26893 participantsModerate
Maternal anxiety
Second trimester routine vs selective ultrasound
no estimate extracted0 studies · 0 participantsUngraded
Birth before 34 weeks' gestation
Second trimester routine vs selective ultrasound
no estimate extracted0 studies · 0 participantsUngraded