Findings

What do systematic reviews say?

3,703 questions · 3,824 findings · 858 reviews

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No studies found 573 · 15%GRADE not reported 383 · 10%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Single computerised session vs single session of case management

Number of days not using drugs (in the past 30 days) at 3 months · summary findings of female review

1 finding from 1 review

Interventions for female drug‐using offenders 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 171 participants
Low

Intravenous magnesium sulphate vs placebo

Change in frequency of vaso‐occlusive painful crises (as measured by pain diary days with significant pain) · people with sickle cell disease

1 finding from 1 review

Magnesium for treating sickle cell disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 104 participants
Moderate

Oral magnesium pidolate vs placebo or no intervention

Change in frequency of vaso‐occlusive painful crises (as measured by pain diary days with significant pain) · people with sickle cell disease

1 finding from 1 review

Magnesium for treating sickle cell disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Low

Ultrasound guidance vs no ultrasound

Block duration (0 to 1 day) · children (≤ 18 years of age) undergoing any type of surgical procedure (open or laparoscopic) for which a neuraxial (spinal, epidural,…

1 finding from 1 review

The use of ultrasound guidance for perioperative neuraxial and peripheral nerve blocks in children 2019 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 460 participants
High

Acetyl‐L‐carnitine vs placebo

General health‐related quality of life · patients with covert or overt hepatic encephalopathy

1 finding from 1 review

Acetyl‐L‐carnitine for patients with hepatic encephalopathy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 67 participants
Very low

Acetyl‐L‐carnitine vs placebo

Number of days in hospital (duration of hospitalisation) · patients with covert or overt hepatic encephalopathy

1 finding from 1 review

Acetyl‐L‐carnitine for patients with hepatic encephalopathy 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Effects of school‐based asthma interventions vs usual care

Experience of daytime and night‐time symptoms ‐ daytime symptoms (daytime symptoms) · children with asthma

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1065 participants
Moderate

Needle aspiration (needle removed immediately after aspiration) vs intercostal tube drainage

Neonatal mortality · patients with pneumothorax in the newborn

The review found no eligible studies for this question.

1 finding from 1 review

Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Needle aspiration (needle or angiocatheter left in situ) vs intercostal tube drainage

Neonatal mortality · patients with pneumothorax in the newborn

The review found no eligible studies for this question.

1 finding from 1 review

Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Duration of upper gastrointestinal bleeding (days) · infants with upper gastrointestinal bleeding

1 finding from 1 review

Pharmacological interventions for prevention and treatment of upper gastrointestinal bleeding in newborn infants 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 104 participants
Very low

Primary (complete) wound closure vs delayed closure

Proportion of wounds which were infection‐free · patients with traumatic wounds due to dog bite

It is very uncertain whether primary closure changes proportion of wounds which were infection free on day 7 compared with delayed closure (very low certainty).

1 finding from 1 review

Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite 2019 · Cochrane Headline outcomes only
RR 0.98 [0.9, 1.07]
1 study · 120 participants
Very low

Robotic‐assisted laparoscopic vs open radical cystectomy

Length of hospital stay · bladder cancer in adults

1 finding from 1 review

Robotic versus open radical cystectomy for bladder cancer in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 541 participants
Low

Omega‐3 fatty acids and antioxidants vs standard diet or placebo

Duration of ICU stay · adults (aged 18 years or older), mechanically ventilated participants with ARDS as defined by the Berlin definition of ARDS or, for older…

1 finding from 1 review

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 639 participants
Very low

Omega‐3 fatty acids and antioxidants vs standard diet or placebo

Days on ventilator · adults (aged 18 years or older), mechanically ventilated participants with ARDS as defined by the Berlin definition of ARDS or, for older…

1 finding from 1 review

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 581 participants
Very low

Omega‐3 fatty acids and antioxidants vs standard diet or placebo

Indices of oxygenation (measured as PaO₂/FiO₂ ratio at day 4) · adults (aged 18 years or older), mechanically ventilated participants with ARDS as defined by the Berlin definition of ARDS or, for older…

1 finding from 1 review

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 659 participants
Very low

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Pruritus · adults with eczema

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 400 participants
Moderate

Zinc tape vs gauze soaked

Ulcer healing · ulceration caused by nerve damage in leprosy

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Very low

Psychological therapies vs controls

Migraine frequency Number of attacks · adults with migraine

1 finding from 1 review

Psychological therapies for the prevention of migraine in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 681 participants
Very low

Continuous local anaesthetic wound infusion vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing elective midline laparotomy for colorectal resection

1 finding from 1 review

Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 511 participants
High

Continuous local anaesthetic wound infusion vs placebo

Pain (VAS scores) on movement at postoperative day 1 Scale from: 0 to 10. · adults undergoing elective midline laparotomy for colorectal resection

1 finding from 1 review

Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 407 participants
Low