Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,372 questions · 3,874 findings · 666 reviews

No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Non‐trauma‐focused psychological intervention for PTSD and SUD or PTSD only vs control intervention

Severity of PTSD symptoms · Individuals with post‐traumatic stress disorder and comorbid substance use disorder
2 findings from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): intermediate term IKDC 2000 (version) score. Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): intermediate term IKDC 2000… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): long term Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): long term Scale from: 0 to 100;… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

QoL · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes quality of life: long‐term KOOS QOL score. Scale 0 to 100; higher… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Pain North Americal Spine Society pain scores. Scale from: 0 to 100 (higher scores indicate less pain). · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes pain: long‐term KOOS Pain score. Scale 0 to 100; higher scores =… compared with microfracture (very low certainty).

1 finding from 1 review

Intervention not reported

Chlamydia prevalence (high risk population) Outcome was prevalence of positive chlamydia tests in repeated cross‐sectional surveys of women tested at sex venues after 4 years of intervention. · healthy adults

The intervention may leads to lower chlamydia prevalence (high risk population) Outcome was prevalence… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐perceived QoL (change from baseline) measured using Peds QL 4.0 Generic Core Scales, scoring 0‐100 points, higher score indicates better quality of life) · children with chronic constipation
1 finding from 1 review

Intervention not reported

Parent‐perceived QoL (change from baseline) measured using PedsQL 4.0 Generic Core Scales, scoring 0‐100 points, higher score indicates better quality of life) · children with chronic constipation
1 finding from 1 review

Intervention not reported

General health‐related quality of life: SF‐36 physical component score (range 0 to 100; higher score = better health state) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review