Cochrane · systematic review · CD010866

Screening for genital chlamydia infection

Low, N, Redmond, S, Uusküla, A, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Sexually Transmitted InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 2 · 50%Moderate 1 · 25%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: healthy adults
4 questions
OutcomeEffectEvidenceStatus / GRADE
Chlamydia prevalence (general population) Outcome was chlamydia test positivity after 3 yearly invitations in intervention clusters vs 1 invitation in control areas. Uptake was too low for chlamydia positivity to be considered an unbiased estimate...
RR 0.96 [0.84, 1.09]1 study · 30122 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Chlamydia prevalence (high risk population) Outcome was prevalence of positive chlamydia tests in repeated cross‐sectional surveys of women tested at sex venues after 4 years of intervention.
RR 0.72 [0.54, 0.98]1 study · 4156 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Incidence of pelvic inflammatory disease (PID) at 12 months (intention‐to‐treat) Outcome was clinically diagnosed PID reported by the participant or extracted from medical records, pharmacy records or hospital discharge coding. Outcome very likely...
RR 0.68 [0.49, 0.94]4 studies · 21686 participantsModerate
Downgraded: risk of bias, imprecision, indirectness
Incidence of epididymitis in men at 12 months (intention‐to‐treat) Outcome was epididymitis diagnosed in hospital and abstracted from hospital discharge coding.
RR 0.8 [0.45, 1.42]1 study · 14980 participantsVery low
Downgraded: risk of bias, imprecision, indirectness