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Evidence found and GRADE certainty

2,536 questions · 2,637 findings · 315 reviews

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No studies found 608 · 23.1%GRADE not reported 488 · 18.5%Very low 688 · 26.1%Low 540 · 20.5%Moderate 249 · 9.4%High 64 · 2.4%

Comparison 1: antibiotic alone or antibiotic with other newborn care interventions vs usual care

Neonatal mortality · neonates with sepsis

Comparison 1: antibiotic alone or antibiotic with other newborn care… showed no clear difference in neonatal mortality ‐ antibiotics alone compared with standard care (moderate certainty).

2 findings from 1 review

Provider‐ or system‐based interventions vs no intervention or another intervention

Posters in clinic displaying influenza vaccination rates to encourage doctors to compete plus postcards to participants compared to posters alone · people aged 60 years and older living in the community

Provider‐ or system‐based interventions showed no clear difference in posters in clinic displaying influenza vaccination rates to… compared with no intervention or another intervention (high certainty).

1 finding from 1 review

Multifactorial interventions vs exercise

Number of people who experienced one or more falls · Older people living in the community

It is very uncertain whether multifactorial interventions changes number of people sustaining one or more falls compared with exercise (very low certainty).

1 finding from 1 review

Multifactorial interventions vs usual care or attention control

Number of people who experienced one or more falls · Older people living in the community

Multifactorial interventions showed no clear difference in number of people sustaining one or more falls compared with usual care or attention control (low certainty).

1 finding from 1 review

Multifactorial interventions vs usual care or attention control

Number of people sustaining one or more fall‐related fractures · Older people living in the community

Multifactorial interventions showed no clear difference in number of people sustaining one or more fall‐related fractures compared with usual care or attention control (low certainty).

1 finding from 1 review

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

Implant failure rate · Participants with an atrophic maxilla who cannot be rehabilitated with conventional dental implants due to lack of bone (including…

The review found no eligible studies for this question.

1 finding from 1 review

Testosterone vs other active intervention

Live birth · women undergoing assisted reproduction

It is very uncertain whether testosterone changes live birth ‐ Testosterone vs estradiol + OCP compared with other active interventions (very low certainty).

2 findings from 1 review

Testosterone vs other active intervention

Miscarriage · women undergoing assisted reproduction

It is very uncertain whether testosterone changes miscarriage ‐ Testosterone vs estradiol compared with other active interventions (very low certainty).

2 findings from 1 review

Testosterone vs other active intervention

Clinical pregnancy rate ‐ Testosterone vs estradiol · women undergoing assisted reproduction

It is very uncertain whether testosterone changes clinical pregnancy rate ‐ Testosterone vs estradiol compared with other active interventions (very low certainty).

1 finding from 1 review

Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms

Exacerbations · people with asthma

Tailored interventions based on sputum eosinophils probably leads to lower number of participants who had one or more exacerbations over the… compared with tailored interventions based on clinical symptoms (moderate certainty).

1 finding from 1 review

One type of occlusal intervention as an adjunct to periodontal therapy vs A different type of occlusal intervention as an adjunct to periodontal therapy (head-to-head)

Outcome not reported · Adults (aged 18 years or older) with a clinical diagnosis of (chronic) periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

An intervention in which one's attention is away from the experience of stress vs no intervention/wait list/placebo/no stress‐reduction intervention

Stress symptoms ( · healthcare workers
3 findings from 1 review

Psychological intervention: structured telephone call (verbal follow‐up and reassurance) vs placebo or no intervention

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Multi‐component intervention vs control

Adverse events: number of people experiencing adverse events (all cause or COPD‐related), serious adverse events, mortality · COPD

Multi‐component intervention showed no clear difference in adverse events: number of people experiencing adverse events (all… compared with control (low certainty).

1 finding from 1 review