Cochrane · systematic review · CD013381
Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD)
Janjua, S, Pike, KC, Carr, R, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 50%Low 5 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Single component intervention compared to control for chronic obstructive pulmonary disease (COPD)
Population: COPD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adherence to pharmacotherapy: number of people completing treatment Single component intervention vs control | OR 0.67 [0.22, 1.99] | 1 study · 55 participants | Low Downgraded: risk of bias, imprecision |
Quality of life: SGRQ total or CCQ Single component intervention vs control | no estimate extracted | 1 study · 212 participants | Very low Downgraded: risk of bias, imprecision |
Hospital service utilisation: number of people admitted to hospital (all cause) Single component intervention vs control | OR 1.47 [0.75, 2.9] | 1 study · 212 participants | Very low Downgraded: risk of bias, imprecision |
Exacerbations: number of people experiencing exacerbations Single component intervention vs control | OR 0.87 [0.51, 1.5] | 2 studies · 267 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events: number of people experiencing adverse events (all cause or COPD‐related), serious adverse events, mortality Single component intervention vs control | OR 0.92 [0.6, 1.41] | 3 studies · 404 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Multi‐component intervention compared to control for chronic obstructive pulmonary disease (COPD)
Population: COPD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adherence to pharmacotherapy: number of people achieving adherence to medication Multi‐component intervention vs control | RR 1.37 [1.18, 1.59] | 4 studies · 446 participants | Low Downgraded: risk of bias |
Quality of life: SGRQ total, SF CRDQ total, CAT total Multi‐component intervention vs control | no estimate extracted | 3 studies · 374 participants | Low Downgraded: risk of bias, imprecision |
Hospital service utilisation: number of people admitted to hospital (all‐cause or COPD‐related) Multi‐component intervention vs control | OR 0.37 [0.22, 0.63] | 2 studies · 877 participants | Low Downgraded: risk of bias |
Exacerbations: number of people experiencing moderate or severe exacerbations Multi‐component intervention vs control | OR 0.97 [0.71, 1.31] | 1 study · 734 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events: number of people experiencing adverse events (all cause or COPD‐related), serious adverse events, mortality Multi‐component intervention vs control | OR 1.05 [0.6, 1.85] | 1 study · 192 participants | Low Downgraded: risk of bias, imprecision |