Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

217 questions · 227 findings · 49 reviews · Schizophrenia

No studies found 5 · 2.2%GRADE not reported 12 · 5.3%Very low 105 · 46.3%Low 46 · 20.3%Moderate 57 · 25.1%High 2 · 0.9%

Cannabidiol vs AMISULPRIDE

Cannabis use · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Cannabidiol vs AMISULPRIDE

Mental state: PANSS total (high = bad) ‐ medium term ‐ not measured · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Horticultural therapy plus standard care vs usual care

Mental state and behaviour DASS21. Scale from: 0 to 84 (high = poor) · patients with schizophrenia

It is very uncertain whether horticultural therapy plus standard care changes mental state and behaviour DASS21. Scale from: 0 to 84 (high = poor) compared with standard care alone (very low certainty).

1 finding from 1 review

STANDARD LOWER DOSE (> 3 to 7.5 mg/day) vs OTHER DOSES

Leaving the study early (2‐10 weeks) vs. standard higher dose (> 7.5‐15 mg/day) · people with the acute phase of schizophrenia

It is very uncertain whether STANDARD LOWER DOSE (> 3 to 7.5 mg/day) changes leaving the study early (2‐10 weeks) vs. standard higher dose (>… compared with OTHER DOSES (very low certainty).

1 finding from 1 review

STANDARD LOWER DOSE (> 3 to 7.5 mg/day) vs OTHER DOSES

Global state: No clinically significant response (as defined by the original studies) · people with the acute phase of schizophrenia

It is very uncertain whether STANDARD LOWER DOSE (> 3 to 7.5 mg/day) changes global state: 1. No clinically significant response in global state… compared with OTHER DOSES (very low certainty).

1 finding from 1 review

STANDARD LOWER DOSE (> 3 to 7.5 mg/day) vs OTHER DOSES

Global state: 1. No clinically significant response in global state (2‐10 weeks) vs. high dose (> 15‐35 mg/day) · people with the acute phase of schizophrenia

It is very uncertain whether STANDARD LOWER DOSE (> 3 to 7.5 mg/day) changes global state: 1. No clinically significant response in global state… compared with OTHER DOSES (very low certainty).

1 finding from 1 review