Quality of life ‐ after 48 months Number of participants: 1325(1 RCT)
1 finding from 1 review
no estimate extracted
Studies not reported
Low
AHI
1 finding from 1 review
no estimate extracted
Studies not reported
Low
All‐cause mortality ‐ up to 80 months Number of participants: 1355(2 RCTs)
Adaptive servo ventilation (ASV) plus best supportive care showed no clear difference in all‐cause mortality ‐ up to 80 months Number of participants: 1355(2… compared with best supportive care alone or inactive control (low certainty).
1 finding from 1 review
RR 0.56 [0.06, 4.93]
Studies not reported
Low
Resolution of symptoms · epidemic keratoconjunctivitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants with resolution of signs within 7 days of treatment (higher is favored) · epidemic keratoconjunctivitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants in whose eyes SEI had disappeared within 21 days of treatment (higher is favored) · epidemic keratoconjunctivitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants who discontinued medication and did not develop rebound SEI within 21 days (higher is favored) · epidemic keratoconjunctivitis
It is very uncertain whether any intervention changes proportion of participants who discontinued medication and did not… compared with steroid alone or plus levofloxacin (very low certainty).
1 finding from 1 review
Proportion of participants who had evidence of adenoviral eradication within 14 days of treatment (higher is favored) · epidemic keratoconjunctivitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants developing a new ulcer · s
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with open‐angle glaucoma
Phacoemulsification + supraciliary microstent surgery probably leads to higher proportion of participants who were medication‐free (not using… compared with phacoemulsification alone (moderate certainty).
1 finding from 1 review
Proportion of participants who required further glaucoma surgery, including laser · people with open‐angle glaucoma
Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants who required further glaucoma surgeryat… compared with phacoemulsification alone (low certainty).
1 finding from 1 review
Rate of visual field progression · people with open‐angle glaucoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants experiencing postoperative complicationsover 24 months (medium‐term) · people with open‐angle glaucoma
Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants experiencing postoperative… compared with phacoemulsification alone (moderate certainty).
1 finding from 1 review
Clinical worsening: need for invasive mechanical ventilation, or death at up to day 28 · people with moderate to severe disease (WHO scale 4–9); all studies contributing results to the summary of findings table included people…
Azithromycin showed no clear difference in worsening of clinical status: participants with clinical… compared with placebo or standard of care alone (moderate certainty).
1 finding from 1 review
Clinical improvement: discharged alive ( · people with moderate to severe disease (WHO scale 4–9); all studies contributing results to the summary of findings table included people…
Azithromycin showed no clear difference in improvement of clinical status: participants discharged alive at day… compared with placebo or standard of care alone (moderate certainty).
1 finding from 1 review
Contrast sensitivity (log contrast threshold) Measured using a Pelli‐Robson chart. Higher scores represent better contrast sensitivity. · people with neovascular AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with neovascular AMD
Radiotherapy combined with anti‐VEGF probably leads to higher loss of 3 or more lines of best‐corrected visual acuity Measured… compared with anti‐VEGF alone (moderate certainty).
1 finding from 1 review
RR 2.11 [1.4, 3.17]
Studies not reported
Moderate
Change in visual acuity (logMAR) ‐ 12 months (negative is better) · people with neovascular AMD
Radiotherapy combined with anti‐VEGF showed no clear difference in change in best corrected visual acuity (logMAR units) Measured using… compared with anti‐VEGF alone (low certainty).
1 finding from 1 review
mean difference 0.1
Studies not reported
Low
Adverse events: death Assessed by: number of participant deaths between a 3‐ and 9‐month · adults with antisocial personality disorder
It is very uncertain whether impulsive lifestyle counselling + treatment‐as‐usual changes adverse events: death Assessed by: number of participant deaths… compared with treatment‐as‐usual alone (very low certainty).
1 finding from 1 review
Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
Cataract surgery with Hydrus microstent probably leads to higher proportion of participants who were medication‐free (not using eye… compared with cataract surgery alone (moderate certainty).
1 finding from 1 review