Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
Resin infiltration may not differ from Sealant for arrest or reversal of approximal carious lesions (RR 0.88, 95% CI 0.4 to 1.91; very low certainty).
1 finding from 1 review
Any planned outcome (sealant retention, caries, etc.) · Patients with premolars/molars requiring pit-and-fissure sealants
No eligible studies compared laser preparation with air abrasion for fissure sealant placement (evidence gap).
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Intervention not reported
Mean DMFT/dmft (caries severity) · Children (<12 years) and adolescents (12-18 years) with type 1 diabetes
The pooled mean DMFT/dmft (caries severity) was 5.7 (SD 3.6) across 5 studies; certainty not graded.
1 finding from 1 review
Dental caries prevalence · Children and adolescents with type 1 diabetes assessed with DMFT
When restricted to studies using DMFT, the pooled dental caries prevalence was 62%.
1 finding from 1 review
Prevalence 0.62
Studies not reported
GRADE not reported
Adverse events · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants
No adverse events were reported in any included study (ungraded, narrative).
1 finding from 1 review
No adverse events (pulpal sensation, post-lasing thermal sensitivity, pulpitis, or other laser-induced pathology) were reported in any of the included studies.
5 studies
GRADE not reported
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
1.23% APF gel may be less effective than Resin infiltration + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.67, 95% CI 0.45 to 0.99; low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
38% SDF + potassium iodide solution (applied annually) may not differ from 5,000-ppm F (1.1% NaF) toothpaste or gel for arrest or reversal of root carious lesions (RR 0.9, 95% CI 0.22 to 3.62; very low certainty).
1 finding from 1 review
Radiographic failure · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in radiographic failure between pulpotomy and pulpectomy in the main analysis (RR 0.79, 95% CI 0.25 to 2.42), with considerable heterogeneity (I2=76%; ungraded).
2 findings from 1 review
Quantitative light-induced fluorescence (QLF), fluorescence loss · Patients (mainly children) with white spot lesions (WSL)
Compared with baseline, CPP-ACP significantly improved white spot lesions on QLF (SMD -0.43, 95% CI -0.79 to -0.07; ungraded).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
1.23% APF gel may be less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.64, 95% CI 0.44 to 0.92; low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
0.2% NaF mouthrinse + supervised toothbrushing may not differ from 1.23% APF gel for arrest or reversal of occlusal carious lesions (RR 0.91, 95% CI 0.68 to 1.22; low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
Resin infiltration + 5% NaF varnish was probably more effective than Sealant for arrest or reversal of occlusal carious lesions (RR 1.61, 95% CI 1.16 to 2.24; moderate certainty).
1 finding from 1 review
Dental erosive wear · Children and adolescents with juvenile idiopathic arthritis (JIA)
No eligible studies reported dental erosive wear, so its association with JIA could not be assessed (evidence gap).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
5% NaF varnish was probably less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.59, 95% CI 0.45 to 0.76; moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single 3-arm RCT found no difference in pulpotomy success between MTA and triple antibiotic paste (both 100%; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 MTA and 20 TAP teeth): 100% clinical and radiographic success in both MTA and TAP at all follow-ups (1-24 months); no difference between groups; not pooled
1 study · 40 participants
GRADE not reported
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
1% chlorhexidine + 1% thymol varnish may not differ from no treatment for arrest or reversal of root carious lesions (RR 1.67, 95% CI 0.44 to 6.31; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
Resin infiltration + 5% NaF varnish may be more effective than no treatment for arrest or reversal of approximal carious lesions (RR 4.59, 95% CI 1.01 to 20.88; very low certainty).
1 finding from 1 review
DMFT/DMFS index (dental caries experience) · Children aged 0-12 years in Finland
The single Finnish study showed lower DMFT/S with OHPP (OR 0.48, 95% CI 0.41 to 0.56; ungraded, single study).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
Sealant + 5% NaF varnish was probably more effective than Sealant for arrest or reversal of occlusal carious lesions (RR 1.69, 95% CI 1.26 to 2.27; moderate certainty).
1 finding from 1 review
Development of >=1 new carious lesion (caries incidence) · Children (high caries risk) with permanent molars requiring pit-and-fissure sealants
Caries incidence was 10% with laser-plus-acid versus 22% with acid-etching at 18 months, a non-significant difference (ungraded, single study).
1 finding from 1 review
Durmus 2017 (Er:YAG laser+acid vs acid-etching): caries incidence 10% (n=8) in the laser-plus-acid group vs 22% (n=18) in the acid-etching group at 18 months; difference not statistically significant (P > 0.05).
1 study · 51 participants
GRADE not reported