Lacunar stroke · European-ancestry adults
Genetically predicted periodontitis was associated with modestly higher odds of lacunar stroke (OR 1.24); ungraded MR, though the FDR-adjusted P was 0.064 for the primary IVW-FE method (ML-adjusted P 0.037).
1 finding from 1 review
OR 1.24 [1.03, 1.49]
Studies not reported
GRADE not reported
Plaque control · Children or adolescents
One RCT reported superior plaque control with a gamified mobile health app versus a conventional method; no effect estimate or GRADE assessment was reported.
1 finding from 1 review
Oral health-related quality of life · people aged 60 years and older living in the community
No statistically significant difference in OHRQoL was reported by periodontal-disease prevalence.
1 finding from 1 review
Peri-implant clinical and radiographic parameters (plaque index, probing depth, bone loss, pro-inflammatory profile) · Adult e-cigarette (ENDS) users with dental implants (incl. male implant-supported prosthesis patients)
Among dental implant patients, e-cigarette users show worse peri-implant parameters (more plaque, worse clinical and radiographic outcomes) than non-smokers (narrative synthesis; ungraded).
1 finding from 1 review
Clinical attachment level (CAL) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Clinical attachment level loss is greater in persons with orofacial cleft than in healthy controls (p<0.00001), but no pooled effect size was reported (ungraded).
1 finding from 1 review
Intervention not reported
Bleeding on Probing (BoP)
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Regular use rate · Children or adolescents
One RCT reported a 72.4% regular-use rate with a gamified mobile health app versus 48.3% with a nongamified intervention; no GRADE assessment was reported.
1 finding from 1 review
Regular use rate 72.4% (gamified mobile app) vs 48.3% (nongamified)
1 study · In one study, the regular use rate was significantly higher (72.4%) in the gamified mobile health app group than in the nongamified intervention group (48.3%). participants
GRADE not reported
Lacunar stroke · adults
No eligible studies were found for the association between pulp and periapical diseases and lacunar stroke in the meta-analysis.
1 finding from 1 review
Salivary flow rate (stimulated) · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general community-dwelling population
Stimulated salivary flow rate was significantly lower in anorexia nervosa patients than controls, but only unstimulated flow was meta-analyzed; this outcome is ungraded.
1 finding from 1 review
Lacunar stroke · European-ancestry adults
Genetically predicted dental caries showed no significant causal association with lacunar stroke (ungraded MR).
1 finding from 1 review
OR 0.92 [0.69, 1.23]
Studies not reported
GRADE not reported
Salivary pH · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general community-dwelling population
Anorexia nervosa is associated with significantly lower salivary pH than healthy controls (MD -0.39, 95% CI -0.54 to -0.24; low certainty).
1 finding from 1 review
Oral health-related quality of life · people aged 60 years and older living in the community
No statistically significant difference in OHRQoL was reported by unemployment rate.
1 finding from 1 review
Oral health-related quality of life · people aged 60 years and older living in the community
No statistically significant difference in OHRQoL was reported by health expenditure per capita.
1 finding from 1 review
Intervention not reported
Tooth loss and dental symptoms (cracked teeth, toothache) associated with e-cigarette use
1 finding from 1 review
Intervention not reported
Plaque index, e-cigarette users versus non-smokers: no significant difference (contrary/null finding)
1 finding from 1 review
Bleeding Index (BI) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Bleeding index is significantly higher in persons with orofacial cleft than in healthy controls (p<0.0001), but no pooled effect size was reported (ungraded).
1 finding from 1 review
Periodontal inflamed surface area (PISA) · adults
Patients with lacunar stroke had a larger periodontal inflamed surface area than those without (MD 849.92); ungraded, no heterogeneity.
1 finding from 1 review
Plaque · Patients with cleft lip and palate (CLP)
Plaque index does not differ significantly between unilateral and bilateral cleft lip and palate (MD -0.13, 95% CI -0.38 to 0.12; ungraded).
1 finding from 1 review
Lacunar stroke · European-ancestry adults
Genetically predicted pulp and periapical diseases were associated with modestly higher odds of lacunar stroke (OR 1.20); ungraded MR, FDR-adjusted P 0.033.
1 finding from 1 review
OR 1.20 [1.03, 1.41]
Studies not reported
GRADE not reported
Intervention not reported
Bacterial count reduction
1 finding from 1 review