Question · asked by 1 review
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy controls: Salivary flow rate (stimulated)
- Population
- Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general community-dwelling population
- Intervention
- Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V)
- Comparison
- Healthy controls
- Outcome
- Salivary flow rate (stimulated)
Stimulated salivary flow rate was significantly lower in anorexia nervosa patients than controls, but only unstimulated flow was meta-analyzed; this outcome is ungraded.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls) Stimulated salivary flow rate · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general… · Clinical dental/oral examination; case-control studies and controlled clinical trials in Europe (mainly Poland, Italy, France, Germany), Australia and the USA Stimulated salivary flow rate was significantly lower in anorexia nervosa patients than controls, but only unstimulated flow was meta-analyzed; this outcome is ungraded. The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025) All outcomes | Stimulated salivary flow rate significantly lower in anorexic patients (Paszynska 2015 Nov 1.20 vs 1.57 ml/min, p=0.005; Paszynska 2018 0.99 vs 1.45 ml/min, p<0.00001); reported narratively, not meta-analyzed | 2 studies · 126 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic treatment: a systematic review… 2025 All outcomes | Up to February 2024 (Abstract); Methods states searched without time restriction up to April 2023 | 19 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.