Bradycardia (requiring pharmacological or pacemaker treatment during the period of study drug administration) · adults undergoing non‐cardiac surgery
1 finding from 1 review
Secondary outcome: acceptability of treatment · depression in adults
1 finding from 1 review
Compliance with treatment · people with schizophrenia with antipsychotic‐induced weight gain
1 finding from 1 review
Compliance with treatment · people with schizophrenia with antipsychotic‐induced weight gain
1 finding from 1 review
Acceptability ‐ total dropouts · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes treatment acceptability ‐dropouts compared with any other pharmacological intervention (very low certainty).
1 finding from 1 review
RR 1.74 [0.99, 3.06]
Studies not reported
Very low
Treatment cessation due to adverse events · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) probably leads to lower pain intensity (VAS 0-100 mm) compared with control (placebo or no treatment) (moderate certainty).
3 findings from 1 review
MD -11.66 [-16.15, -7.17]
10 studies · 685 participants
Moderate
MD -21.19 [-28.31, -14.06]
12 studies · 1012 participants
Moderate
MD -24.27 [-31.44, -17.11]
9 studies · 535 participants
Moderate
Quality of life or participant satisfaction · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review
Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review
Time off school or work · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Any serious adverse event of treatment · people with traumatic head injuries
1 finding from 1 review
Any serious adverse event of treatment count of events · people with traumatic head injuries
Antiepileptic drugs showed no clear difference in any serious adverse event of treatment count of events compared with placebo or standard care (low certainty).
1 finding from 1 review
Any serious adverse event of treatment · people with traumatic head injuries
1 finding from 1 review
Depression symptoms ‐ short‐term · health problem or population
1 finding from 1 review
Depression remission · health problem or population
Summary of findings table ‐ Psychological treatment showed no clear difference in depression remission ‐ short term compared with control (low certainty).
1 finding from 1 review
All‐cause mortality ‐ short‐term · health problem or population
It is very uncertain whether summary of findings table ‐ Psychological treatment changes all‐cause mortality ‐ short‐term compared with control (very low certainty).
1 finding from 1 review
Cardiovascular mortality · health problem or population
Summary of findings table ‐ Psychological treatment showed no clear difference in cardiovascular mortality ‐ long‐term compared with control; GRADE not reported.
1 finding from 1 review
Use of pharmacological pain relief ‐ not reported · pain management in labour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events as N of participants with at least one adverse event objective · patients with the treatment of cocaine dependence
It is very uncertain whether summary of findings table – disulfiram changes any adverse events (number of participants who experienced at least… compared with placebo or no pharmacological treatment (very low certainty).
1 finding from 1 review