Findings

What do systematic reviews say?

324 questions · 341 findings · 54 reviews · Headline outcomes only

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No studies found 120 · 35.2%GRADE not reported 9 · 2.6%Very low 97 · 28.4%Low 80 · 23.5%Moderate 25 · 7.3%High 10 · 2.9%

Dietary advice vs dietary advice plus oral nutritional supplements

Change in fat‐free mass (kg) · adults with disease‐related malnutrition

1 finding from 1 review

Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 187 participants
Low

Dietary advice plus supplements vs no advice

Change in fat‐free mass (kg) · adults with disease‐related malnutrition

1 finding from 1 review

Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 262 participants
Low

Dietary advice plus supplements vs no dietary advice plus no supplements

Change in fat‐free mass (kg) · adults with disease‐related malnutrition

1 finding from 1 review

Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 130 participants
Very low

Dietary advice vs no advice

Change in fat‐free mass (kg) · adults with disease‐related malnutrition

1 finding from 1 review

Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 98 participants
Low

Cell signal transducers vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Glutamate modulators vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Moderate

Glutamate modulators vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · children and adolescents with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Antioxidants vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Low

Opioid antagonists vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 51 participants
Low

Selective serotonin reuptake inhibitors vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Antioxidants vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · children with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 6 participants
Low

Antipsychotics vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Low

Exercise plus usual care vs usual care

Lean body mass · cancer cachexia in adults

1 finding from 1 review

Exercise for cancer cachexia in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Multimodal intervention (exercise plus other interventions) plus usual care vs usual care

Lean body mass · cancer cachexia in adults

1 finding from 1 review

Exercise for cancer cachexia in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

Non‐pharmaceutical interventions vs non‐pharmacological intervention

Body weight / BMI · obese women with subfertility

1 finding from 1 review

Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 11 participants
Very low

Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes

Adverse effects: abdominal mass · adults and children with cystic fibrosis

1 finding from 1 review

Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Aldosterone antagonists vs placebo or usual care

Left ventricular mass · people with chronic kidney disease requiring dialysis

1 finding from 1 review

Aldosterone antagonists for people with chronic kidney disease requiring dialysis 2021 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 562 participants
Low

Any weight loss intervention vs usual care or control

Body‐mass index (BMI) · people with CKD who are overweight or obese

1 finding from 1 review

Interventions for weight loss in people with chronic kidney disease who are overweight or obese 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 100 participants
Very low

Pedometer intervention vs alternative physical activity intervention

Body‐mass index (BMI) · employees

1 finding from 1 review

Workplace pedometer interventions for increasing physical activity 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 144 participants
Very low

Pedometer intervention vs minimal intervention

Body‐mass index (BMI) · employees

1 finding from 1 review

Workplace pedometer interventions for increasing physical activity 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 486 participants
Low