Cochrane · systematic review · CD012798
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis
Gilchrist, FJ, Green, J, Carroll, W · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
3
Included studies
NR
No studies 3 · 50%Ungraded 0 · 0%Very low 3 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsSummary of findings ‐ high‐dose pancreatic enzymes compared with low‐dose pancreatic enzymes
Population: children and adults with cystic fibrosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time taken from start of treatment until the resolution of DIOS Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes | no estimate extracted | NR | No studies |
Treatment failure rate Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes | no estimate extracted | NR | No studies |
Adherence Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes | no estimate extracted | NR | No studies |
Episodes of acute DIOS Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes | no estimate extracted | 1 study · 20 participants | Very low |
Adverse effects: abdominal mass Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adverse effects: abdominal pain Summary of findings ‐ high‐dose pancreatic enzymes vs low‐dose pancreatic enzymes | no estimate extracted | 1 study · 20 participants | Very low Downgraded: risk of bias, imprecision, indirectness |