Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Enhancing vaccination access vs no intervention or another intervention

Home visit with encouragement to receive influenza vaccination compared to home visit with safety intervention · people aged 60 years and older living in the community

Enhancing vaccination access showed no clear difference in home visit with encouragement to receive influenza vaccination… compared with no intervention or another intervention (high certainty).

1 finding from 1 review

Enhancing vaccination access vs no intervention or another intervention

Home visit by nurse or group sessions with encouragement to receive influenza vaccination plus care plan developed with physician compared to no intervention · people aged 60 years and older living in the community
1 finding from 1 review

Provider‐ or system‐based interventions vs no intervention or another intervention

Posters in clinic displaying influenza vaccination rates to encourage doctors to compete plus postcards to participants compared to no intervention · people aged 60 years and older living in the community

Provider‐ or system‐based interventions leads to higher posters in clinic displaying influenza vaccination rates to… compared with no intervention or another intervention (high certainty).

1 finding from 1 review

Provider‐ or system‐based interventions vs no intervention or another intervention

Posters in clinic displaying influenza vaccination rates to encourage doctors to compete plus postcards to participants compared to posters alone · people aged 60 years and older living in the community

Provider‐ or system‐based interventions showed no clear difference in posters in clinic displaying influenza vaccination rates to… compared with no intervention or another intervention (high certainty).

1 finding from 1 review

Parent‐ and clinician‐mediated intervention vs clinician‐mediated intervention alone

Expressive language (number of words; standard scores; MLUw; NDW; IPSyn; frequency of unique targets; % target talk) · children with Down syndrome aged between birth and six years
1 finding from 1 review

Intervention not reported

Percentage of participants not requiring postoperative opioids over initial 72 hours · adults aged ≥ 18 years undergoing elective surgery at any surgical site

The review found no eligible studies for this question.

1 finding from 1 review

Laparoscopic fundoplication vs medical management

(5 years or more) · Patients with gastro‐oesophageal reflux disease (GORD) in adults

It is very uncertain whether laparoscopic fundoplication changes (5 years or more) compared with medical management (very low certainty).

1 finding from 1 review

Combination chemotherapy vs single‐agent chemotherapy

Overall survival (3 years) · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery

It is very uncertain whether combination chemotherapy changes overall survival (3 years) compared with single‐agent chemotherapy (very low certainty).

1 finding from 1 review

Combination chemotherapy vs single‐agent chemotherapy

Disease-free survival · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery

It is very uncertain whether combination chemotherapy changes disease‐free survival (3 years) compared with single‐agent chemotherapy (very low certainty).

1 finding from 1 review