Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,703 questions · 3,824 findings · 858 reviews

No studies found 573 · 15%GRADE not reported 383 · 10%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Oral iron sulphate vs oral iron hydroxide polymaltose complex

Serious adverse events ‐ active or inactive disease (14 days) · IBD patients

It is very uncertain whether oral iron sulphate changes serious adverse events ‐ active or inactive disease (14 days) compared with oral iron hydroxide polymaltose complex (very low certainty).

1 finding from 1 review

Standard treatment plus systemic corticosteroids vs usual care

Severity of pain on day 3 · patients age 10 years and older with periorbital or orbital cellulitis

It is very uncertain whether standard treatment plus systemic corticosteroids changes severity of pain on day 3 compared with standard treatment alone (very low certainty).

1 finding from 1 review

Hydroxychloroquine (HCQ) vs placebo or usual care

Negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from enrolmentd · adults with mild to severe COVID‐19

Hydroxychloroquine (HCQ) showed no clear difference in negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from… compared with standard care or placebo (low certainty).

1 finding from 1 review

Hydroxychloroquine (HCQ) vs placebo

Development of confirmed COVID‐19 at 14 days from enrolment · people who have been exposed to SARS‐CoV‐2

It is very uncertain whether hydroxychloroquine (HCQ) changes development of confirmed COVID‐19 at 14 days from enrolment compared with placebo (very low certainty).

1 finding from 1 review