Cochrane · systematic review · CD013535
Corticosteroids for periorbital and orbital cellulitis
Kornelsen, E, Mahant, S, Parkin, P, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Standard treatment plus systemic corticosteroids compared to standard treatment alone for periorbital and orbital cellulitis
Population: patients age 10 years and older with periorbital or orbital cellulitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Length of hospital stay Standard treatment plus systemic corticosteroids vs standard treatment alone | MD 4.3 | 1 study · 21 participants | Very low Downgraded: risk of bias, imprecision |
Preservation of visual acuity Standard treatment plus systemic corticosteroids vs standard treatment alone | RR 1 [0.82, 1.22] | 1 study · 21 participants | Very low Downgraded: risk of bias, imprecision |
Severity of pain on day 3 Standard treatment plus systemic corticosteroids vs standard treatment alone | no estimate extracted | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision |
Duration of time requiring intravenous antibiotics Standard treatment plus systemic corticosteroids vs standard treatment alone | MD 3 | 1 study · 21 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Need for surgical intervention Standard treatment plus systemic corticosteroids vs standard treatment alone | RR 1 [0.11, 9.23] | 1 study · 21 participants | Very low Downgraded: risk of bias, imprecision |
Adverse effects: exposure keratopathy Standard treatment plus systemic corticosteroids vs standard treatment alone | RR 1.2 [0.4, 3.63] | 1 study · 21 participants | Very low Downgraded: risk of bias, imprecision |
Return visit to health care (not reported) Standard treatment plus systemic corticosteroids vs standard treatment alone | no estimate extracted | NR | No studies |