Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Arm support combined with alternative mouse vs conventional mouse alone

Incidence of neck/shoulder disorder Questionnaire followed by medical examination · office workers

Arm support combined with alternative mouse probably leads to lower incidence of neck or shoulder disorder Questionnaire followed by… compared with conventional mouse alone (moderate certainty).

1 finding from 1 review

Arm support combined with alternative mouse vs conventional mouse alone

Incidence of right upper extremity disorder Questionnaire followed by medical examination · office workers

Arm support combined with alternative mouse showed no clear difference in incidence of right upper extremity disorder Questionnaire followed… compared with conventional mouse alone (moderate certainty).

1 finding from 1 review

Arm support with conventional mouse vs conventional mouse alone

Incidence of upper body disorders Questionnaire followed by medical examination · office workers

Arm support with conventional mouse showed no clear difference in incidence of upper body disorders Questionnaire followed by medical… compared with conventional mouse alone (low certainty).

1 finding from 1 review

Arm support with conventional mouse vs conventional mouse alone

Incidence of neck/shoulder disorder Questionnaire followed by medical examination · office workers

Arm support with conventional mouse showed no clear difference in incidence of neck or shoulder disorder Questionnaire followed by… compared with conventional mouse alone (low certainty).

1 finding from 1 review

Arm support with conventional mouse vs conventional mouse alone

Incidence of right upper extremity disorder Questionnaire followed by medical examination · office workers

Arm support with conventional mouse showed no clear difference in incidence of right upper extremity disorders Questionnaire followed… compared with conventional mouse alone (moderate certainty).

1 finding from 1 review

Intervention not reported

Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Physical and cognitive therapy vs usual care

Cognitive functioning b) Executve functioning (DEX score) (scores range from 0 to 80. Lower scores indicate better functioning) (DEX) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

Anaemia · general population older than 2 years of age (including pregnant women), in Kenya and Mexico

It is very uncertain whether provision of maize flour or maize flour products fortified with iron… changes anaemia (defined as haemoglobin (Hb) below WHO cut‐off, adjusted for… compared with unfortified maize flours or maize flour products (very low certainty).

1 finding from 1 review

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life) · patients with fibromyalgia

Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty).

1 finding from 1 review

FIBRINOGEN: Therapeutic trials: intervention vs inactive control

All‐cause mortality Up to 28 days following admission · the prevention and treatment of bleeding in patients without haemophilia

FIBRINOGEN: Therapeutic trials: intervention showed no clear difference in all‐cause mortality Up to 28 days following admission compared with inactive Control (moderate certainty).

1 finding from 1 review