Question · asked by 1 review
Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo: Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life)
- Population
- patients with fibromyalgia
- Intervention
- Serotonin and noradrenaline reuptake inhibitors (SNRI)
- Comparison
- placebo
- Outcome
- Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life)
Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Serotonin noradrenaline reuptake inhibitors vs placebo Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life) · people with fibromyalgia Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty). Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia (2018) · Cochrane Headline outcomes only | no estimate extracted | 14 studies · 6861 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.