Cochrane · systematic review · CD009260

Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)

Reichow, B, Hume, K, Barton, EE, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)

Population: patients with young children (less than six years old) with autism spectrum disorders (ASD)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Adaptive behavior Measured by: Vineland Adaptive Behavior Scales (parent‐reported scale; mean = 100 (SD = 15); higher score equates to better outcomes)
no estimate extracted5 studies · 202 participantsLow
Downgraded: risk of bias, imprecision, publication bias
Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms)
no estimate extracted2 studies · 81 participantsVery low
Downgraded: imprecision, publication bias
Adverse effects Measured by: worsening of adaptive behavior or autism symptom severity
no estimate extractedNRNo studies
Intelligence Measured by: standardized IQ tests (mean = 100 (SD = 15); higher scores indicate higher IQ)
no estimate extracted5 studies · 202 participantsLow
Downgraded: risk of bias, imprecision, publication bias
Communication and language skills: expressive language Measured by: standardized measures of expressive language (higher scores indicate better expressive language skills)
no estimate extracted4 studies · 165 participantsLow
Downgraded: risk of bias, imprecision, publication bias
Communication and language skills: receptive language Measured by: standardized measures of receptive language (higher scores indicate better receptive language skills)
no estimate extracted4 studies · 164 participantsLow
Downgraded: risk of bias, imprecision, publication bias
Problem behavior Measured by: standardized parent‐report measures and checklists (lower scores indicate lower levels or less severe problem behavior)
no estimate extracted2 studies · 67 participantsVery low
Downgraded: imprecision, publication bias