Cochrane · systematic review · CD009260
Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)
Reichow, B, Hume, K, Barton, EE, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyEarly intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)
Population: patients with young children (less than six years old) with autism spectrum disorders (ASD)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adaptive behavior Measured by: Vineland Adaptive Behavior Scales (parent‐reported scale; mean = 100 (SD = 15); higher score equates to better outcomes) | no estimate extracted | 5 studies · 202 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) | no estimate extracted | 2 studies · 81 participants | Very low Downgraded: imprecision, publication bias |
Adverse effects Measured by: worsening of adaptive behavior or autism symptom severity | no estimate extracted | NR | No studies |
Intelligence Measured by: standardized IQ tests (mean = 100 (SD = 15); higher scores indicate higher IQ) | no estimate extracted | 5 studies · 202 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Communication and language skills: expressive language Measured by: standardized measures of expressive language (higher scores indicate better expressive language skills) | no estimate extracted | 4 studies · 165 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Communication and language skills: receptive language Measured by: standardized measures of receptive language (higher scores indicate better receptive language skills) | no estimate extracted | 4 studies · 164 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Problem behavior Measured by: standardized parent‐report measures and checklists (lower scores indicate lower levels or less severe problem behavior) | no estimate extracted | 2 studies · 67 participants | Very low Downgraded: imprecision, publication bias |
Early intensive behavioral intervention for increasing functional behaviors and skills for young children with autism spectrum disorders (ASD)
Population: Young children with ASD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adaptive behavior (composite) Vineland Adaptive Behavior Scales | no estimate extracted | 5 studies · 171 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Early intensive behavioral intervention for decreasing psychopathology and symptom severity for young children with autism spectrum disorders (ASD)
Population: Young children with ASD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Symptom severity Autism diagnostic instruments and screeners1 | no estimate extracted | 2 studies · 70 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Problem behavior Standardized behavior checklists6 | no estimate extracted | 2 studies · 39 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Early intensive behavioral intervention for increasing intelligence and cognition for young children with autism spectrum disorders (ASD)
Population: Young children with ASD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
IQ Standardized tests of intelligence | no estimate extracted | 5 studies · 172 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Early intensive behavioral intervention for increasing communication and language skills for young children with autism spectrum disorders (ASD)
Population: Young children with ASD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Expressive Language Reynell | no estimate extracted | 4 studies · 124 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Receptive Language Reynell | no estimate extracted | 4 studies · 124 participants | Low Downgraded: risk of bias, imprecision, publication bias |
VABS Communication Domain Vineland Adaptive Behavior Scales | no estimate extracted | 5 studies · 171 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Early intensive behavioral intervention for increasing social competence and skills for young children with autism spectrum disorders (ASD)
Population: Young children with ASD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
VABS Socialization Domain Vineland Adaptive Behavior Scales | no estimate extracted | 5 studies · 171 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Early intensive behavioral intervention for increasing quality of life for young children with autism spectrum disorders (ASD)
Population: Young children with ASD and their parents
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
VABS Daily Living Skills Vineland Adaptive Behavior Scales | no estimate extracted | 5 studies · 171 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Parental Stress Questionnaire on Resources and Stress Friedrich‐short form | no estimate extracted | 1 study · 44 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Parental Anxiety and Depression Hospital Anxiety and Depression Scale | no estimate extracted | 1 study · 44 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Parental Positive Perceptions Kansas Inverntory of Parental Perceptions Positive Contributions Scale | no estimate extracted | 1 study · 44 participants | Low Downgraded: risk of bias, imprecision, publication bias |