Cochrane · systematic review · CD009103
Interventions for improving modifiable risk factor control in the secondary prevention of stroke
Bridgwood, B, Lager, KE, Mistri, AK, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
14
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 35.7%Moderate 9 · 64.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Educational or behavioural interventions for patients compared to usual care for improving modifiable risk factor control in the secondary prevention of stroke
Population: The trials included a total of 33,840 participants with cerebrovascular disease. The mean or median age of participants ranged from 60 years to 74.3 years. Nine studies included participants with diagnoses of ischaemic stroke; six studies included participants with either ischaemic or haemorrhagic stroke; one focused on lacunar strokes; two did not specify stroke subtype; four included participants with TIA only and 19 trials included a broader range of participants with a diagnosis of either stroke or TIA.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean systolic blood pressure Educational or behavioural interventions for patients vs usual care | no estimate extracted | 11 studies · 1398 participants | Moderate Downgraded: inconsistency |
Mean diastolic blood pressure Educational or behavioural interventions for patients vs usual care | no estimate extracted | 11 studies · 1398 participants | Moderate Downgraded: inconsistency |
Blood pressure target achievement Educational or behavioural interventions for patients vs usual care | OR 1.34 [0.7, 2.59] | 3 studies · 266 participants | Moderate Downgraded: inconsistency |
Medication adherence Educational or behavioural interventions for patients vs usual care | no estimate extracted | 13 studies · 33762 participants | Low Downgraded: inconsistency |
Mean low density lipoprotein Educational or behavioural interventions for patients vs usual care | no estimate extracted | 4 studies · 495 participants | Moderate Downgraded: imprecision, inconsistency |
Mean HbA1c Educational or behavioural interventions for patients vs usual care | no estimate extracted | 1 study · 70 participants | Low Downgraded: imprecision, inconsistency |
Mean BMI Educational or behavioural interventions for patients vs usual care | no estimate extracted | 2 studies · 127 participants | Moderate Downgraded: imprecision, inconsistency |
Organisational interventions compared to usual care for improving modifiable risk factor control in the secondary prevention of stroke
Population: The trials included a total of 33,840 participants with cerebrovascular disease. The mean or median age of participants ranged from 60 years to 74.3 years. Nine studies included participants with diagnoses of ischaemic stroke; six studies included participants with either ischaemic or haemorrhagic stroke; one focused on lacunar strokes; two did not specify stroke subtype; four included participants with TIA only and 19 trials included a broader range of participants with a diagnosis of either stroke or TIA.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean systolic blood pressure Organisational interventions vs usual care | no estimate extracted | 16 studies · 17490 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Mean diastolic blood pressure Organisational interventions vs usual care | no estimate extracted | 14 studies · 17178 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Blood pressure target achievement Organisational interventions vs usual care | OR 1.44 [1.09, 1.9] | 13 studies · 23631 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Medication adherence Organisational interventions vs usual care | no estimate extracted | 8 studies · 5384 participants | Low Downgraded: risk of bias |
Mean low density lipoprotein Organisational interventions vs usual care | no estimate extracted | 5 studies · 1008 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Mean HbA1C Organisational interventions vs usual care | no estimate extracted | 4 studies · 554 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Mean BMI Organisational interventions vs usual care | no estimate extracted | 5 studies · 1089 participants | Low Downgraded: risk of bias, imprecision, inconsistency |