Findings

What do systematic reviews say?

2,922 questions · 3,118 findings · 513 reviews

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No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Intervention not reported

Pain intensity various scales short‐term · adults with chronic low‐back pain

1 finding from 1 review

Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 93 participants
Moderate

Intervention not reported

Pain intensity various scales intermediate‐term · adults with chronic low‐back pain

1 finding from 1 review

Behavioural treatment for chronic low‐back pain 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 82 participants
Moderate

Intervention not reported

Other outcomes [2] (continuous outcomes) Smoking, dementia, obesity, hypertension, insomnia, anxiety, asthma, phobia)

1 finding from 1 review

Placebo interventions for all clinical conditions 2010 · Cochrane Headline outcomes only
no estimate extracted
41 studies · 1317 participants
Low

Intervention not reported

Sharp reduction of 5 km/h in median speed on experimental roads after program launch. No further reduction observed despite intensified enforcement. However reduction sustained throughout the 15 month trial period.

1 finding from 1 review

Speed cameras for the prevention of road traffic injuries and deaths 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Intervention not reported

Pain intensity Various validated pain scales · Patients with osteoarthritis of the knee

The intervention showed no clear difference in pain intensity Various validated pain scales (low certainty).

1 finding from 1 review

Joint lavage for osteoarthritis of the knee 2010 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 567 participants
Low

Intervention not reported

Pain intensity Various validated pain scales · Patients with osteoarthritis of the knee

The intervention showed no clear difference in pain intensity Various validated pain scales (low certainty).

1 finding from 1 review

Joint lavage for osteoarthritis of the knee 2010 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 380 participants
Low

CHLORPROMAZINE vs haloperidol

Adverse effects ‐ cardiovascular ‐ hypotension · patients with psychosis‐induced aggression or agitation

It is very uncertain whether CHLORPROMAZINE changes adverse effects ‐ cardiovascular ‐ hypotension compared with HALOPERIDOL (very low certainty).

1 finding from 1 review

Chlorpromazine for psychosis induced aggression or agitation 2010 · Cochrane Headline outcomes only
RR 5 [0.26, 96.13]
1 study · 30 participants
Very low

bed rest vs advice to stay active

Pain intensity various scales short‐term · Patients with acute low‐back pain

1 finding from 1 review

Advice to rest in bed versus advice to stay active for acute low‐back pain and sciatica 2010 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 480 participants
Low

bed rest vs advice to stay active

Pain intensity, long‐term · Patients with acute low‐back pain

1 finding from 1 review

Advice to rest in bed versus advice to stay active for acute low‐back pain and sciatica 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 393 participants
Moderate

bed rest vs advice to stay active

Pain intensity various scales short‐term · patients with sciatica

1 finding from 1 review

Advice to rest in bed versus advice to stay active for acute low‐back pain and sciatica 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 346 participants
Moderate

bed rest vs advice to stay active

Pain intensity, long‐term · patients with sciatica

1 finding from 1 review

Advice to rest in bed versus advice to stay active for acute low‐back pain and sciatica 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 330 participants
Moderate

Oral celecoxib (COX-2 inhibitor) vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Oral celecoxib (COX-2 inhibitor) showed no clear difference in pain intensity (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review

Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes
6 weeks
MD 0.03 [-0.40, 0.45]
1 study · 68 participants
GRADE not reported

Naproxen vs placebo

Oral naproxen (NSAID) led to lower pain intensity (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review

Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes
6 weeks
MD -1.70 [-2.14, -1.25]
1 study · 68 participants
GRADE not reported

Oral glucosamine hydrochloride/chondroitin sulphate vs placebo

Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in pain intensity (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review

Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes
3 months
MD -0.70 [-2.16, 0.76]
1 study · 45 participants
GRADE not reported

Summary of findings: 5 mg/day vs placebo

Pain intensity (0‐10cm visual analogue scale) · rotator cuff disease

1 finding from 1 review

Topical glyceryl trinitrate for rotator cuff disease 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Intervention not reported

Muscle strength Isometric extension · patients with patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 305 participants
High

Intervention not reported

Muscle strength Isometric extension · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 74 participants
Moderate

Intervention not reported

Muscle strength Isometric extension · patients with Rheumatoid Arthritis

1 finding from 1 review

Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis 2009 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Low

AFI vs SDVP: summary of findings table

Admission to neonatal intensive care unit · pregnant women to prevent adverse pregnancy outcome

AFI showed no clear difference in admission to neonatal intensive care unit compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
RR 1.04 [0.85, 1.26]
5 studies · 3226 participants
Moderate

Oral paracetamol vs placebo

At least 50% reduction in pain · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 4 hours (using pain intensity… compared with placebo; GRADE not reported.

2 findings from 1 review

Paracetamol for pain relief after surgical removal of lower wisdom teeth 2007 · Cochrane All outcomes
4 hours
RR 4.87 [2.83, 8.37]
17 studies · 1658 participants
GRADE not reported
Paracetamol for pain relief after surgical removal of lower wisdom teeth 2007 · Cochrane All outcomes
6 hours
RR 3.41 [2.34, 4.97]
13 studies · 1184 participants
GRADE not reported