Findings

What do systematic reviews say?

3,231 questions · 3,354 findings · 394 reviews

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No studies found 803 · 23.9%GRADE not reported 267 · 8%Very low 757 · 22.6%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Minoxidil 2% vs minoxidil 5%

Adverse events · women with FPHL

Minoxidil 2% showed no clear difference in adverse events compared with minoxidil 5% (low certainty).

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
RR 1.02 [0.91, 1.2]
4 studies · 1006 participants
Low

Minoxidil 2% vs minoxidil 5%

Proportion of participants with investigator‐rated clinically significant hair regrowth · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 586 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Change from baseline to study conclusion in total hair count · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 631 participants
Low

Minoxidil 2% vs minoxidil 5%

Degree of hair shedding from baseline to the end of the study · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Minoxidil 2% vs minoxidil 5%

Cosmetic appearance of the hair or participant satisfaction · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Change in quality (or pattern) of hair regrowth (e.g. thickness) · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Moderate

Minoxidil 2% vs minoxidil 5%

Proportion of participants with self‐rated clinically significant hair regrowth · women with FPHL

1 finding from 1 review

Interventions for female pattern hair loss 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 322 participants
Low

Antibiotics vs placebo

Minor adverse events in sexual partner · sexual partners of women with bacterial vaginosis

Any antibiotic treatment may leads to higher minor adverse events in sexual partner compared with placebo (low certainty).

1 finding from 1 review

Antibiotic treatment for the sexual partners of women with bacterial vaginosis 2016 · Cochrane Headline outcomes only
RR 2.55 [1.55, 4.18]
3 studies · 477 participants
Low

Laser photocoagulation vs control

Progression of retinopathy · people with diabetic retinopathy

Laser photocoagulation may leads to lower progression of diabetic retinopathy compared with control (low certainty).

1 finding from 1 review

Laser photocoagulation for proliferative diabetic retinopathy 2014 · Cochrane Headline outcomes only
RR 0.49 [0.37, 0.64]
4 studies · 8331 participants
Low

Milrinone vs dobutamine

All‐cause mortality · adults with low cardiac output syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nitinol archwire vs Titinol archwire

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether nitinol archwire changes amount of crowding (change) up to 37 weeks compared with titinol archwire (very low certainty).

1 finding from 1 review

Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
up to 37 weeks
MD -0.28 [-0.89, 0.33]
1 study · 40 participants
Very low

Topical quinolone vs quinolones

Resolution of ear discharge ‐ measured at 1 to 2 weeks · people (of any age) with CSOM

Topical quinolone may leads to higher resolution of ear discharge ‐ 1 to 2 weeks compared with oral quinolone (low certainty).

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 1.48 [1.24, 1.76]
3 studies · 285 participants
Low

Topical quinolone vs quinolones

Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Health‐related quality of life · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Ear pain (otalgia) or discomfort or local irritation · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Hearing · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Serious complications · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Suspected ototoxicity · people (of any age) with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 265 participants
Very low

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel

Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found