Topical quinolone vs quinolones: Resolution of ear discharge ‐ measured at 1 to 2 weeks
- Population
- people (of any age) with CSOM
- Intervention
- Topical quinolone
- Comparison
- quinolones
- Outcome
- Resolution of ear discharge ‐ measured at 1 to 2 weeks
Topical quinolone may leads to higher resolution of ear discharge ‐ 1 to 2 weeks compared with oral quinolone (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical quinolone vs oral quinolone Resolution of ear discharge ‐ 1 to 2 weeks · people (of any age) with CSOM Topical quinolone may leads to higher resolution of ear discharge ‐ 1 to 2 weeks compared with oral quinolone (low certainty). Topical versus systemic antibiotics for chronic suppurative otitis media (2021) · Cochrane Headline outcomes only | RR 1.48 [1.24, 1.76] | 3 studies · 285 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Topical quinolone vs intramuscular gentamicin · adults with CSOM · 1 review
- Topical quinolone vs povidone‐iodine · chronic suppurative otitis media · 1 review
- Topical quinolone vs oral amoxicillin‐clavulanic acid combination · adults with CSOM · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.