Cochrane · systematic review · CD011701
Antibiotic treatment for the sexual partners of women with bacterial vaginosis
Amaya‐Guio, J, Viveros‐Carreño, DA, Sierra‐Barrios, EM, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Sexually Transmitted InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 33.3%Low 2 · 16.7%Moderate 0 · 0%High 6 · 50%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Any antibiotic treatment versus placebo
Population: sexual partners of women with bacterial vaginosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Recurrence Any antibiotic treatment vs placebo | RR 1 [0.67, 1.52] | 3 studies · 372 participants | Very low Downgraded: imprecision |
Clinical improvement Any antibiotic treatment vs placebo | RR 1.02 [0.94, 1.11] | 3 studies · 590 participants | High |
Clinical improvement Any antibiotic treatment vs placebo | RR 0.98 [0.9, 1.07] | 4 studies · 572 participants | High |
Symptomatic improvement during the first week Any antibiotic treatment vs placebo | RR 1.06 [1, 1.12] | 3 studies · 577 participants | High |
Symptomatic improvement Any antibiotic treatment vs placebo | RR 0.93 [0.84, 1.03] | 2 studies · 444 participants | High |
Symptomatic improvement Any antibiotic treatment vs placebo | RR 1.03 [0.9, 1.17] | 2 studies · 296 participants | High |
Minor adverse events in sexual partner Any antibiotic treatment vs placebo | RR 2.55 [1.55, 4.18] | 3 studies · 477 participants | Low Downgraded: imprecision |
Any antibiotic treatment versus no intervention
Population: sexual partners of women with bacterial vaginosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Recurrence Any antibiotic treatment vs no intervention | RR 1.71 [0.65, 4.55] | 1 study · 51 participants | Very low Downgraded: risk of bias, imprecision |
Clinical improvement Any antibiotic treatment vs no intervention | RR 0.93 [0.7, 1.25] | 2 studies · 152 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Symptomatic improvement Any antibiotic treatment vs no intervention | RR 0.66 [0.39, 1.11] | 1 study · 70 participants | Very low Downgraded: risk of bias, imprecision |
Any antibiotic treatment versus placebo
Population: sexual partners of women with bacterial vaginosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Recurrence Any antibiotic treatment vs placebo | RR 1.28 [0.68, 2.43] | 1 study · 218 participants | Low Downgraded: imprecision |
Clinical improvement during the first week Any antibiotic treatment vs placebo | RR 0.99 [0.96, 1.03] | 4 studies · 712 participants | High |