Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Intermittent iron supplementation (alone or with any other micronutrients) vs no supplementation or placebo

Anaemia · adolescent and adult menstruating women

Intermittent iron supplementation (alone or with any other… may leads to lower anaemia (haemoglobin concentration below a cut‐off defined by the… compared with no supplementation or placebo (low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs any daily iron supplementation

Anaemia · adolescent and adult menstruating women

Intermittent iron supplementation showed no clear difference in anaemia (haemoglobin concentration below a cut‐off defined by the… compared with daily iron supplementation (moderate certainty).

1 finding from 1 review

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Anaemia · general population of all age groups (including pregnant women) from any country, over two years of age

Rice fortified with iron alone or in combination with other… may leads to lower anaemia (defined as haemoglobin below the WHO cut‐off, adjusted for… compared with unfortified rice (no micronutrients added) (low certainty).

1 finding from 1 review

Corticosteroids vs no corticosteroid use

All‐cause mortality Up to 28 days following admission · individuals with influenza

It is very uncertain whether corticosteroid therapy changes number of deaths at 30 days following admission (30‐day mortality)a compared with no corticosteroid therapy (very low certainty).

1 finding from 1 review

Intranasal corticosteroids vs placebo

Health outcomes Peak expiratory flow readings (higher readings indicate better peak flow) · adults and children > 12 with non‐allergic rhinitis

It is very uncertain whether intranasal corticosteroids changes objective measurement of airflow: peak flow rate (expiratory) compared with placebo (very low certainty).

1 finding from 1 review