Search review questions

Caries severity (mean DMFT) · 12-year-old children (permanent dentition) in Africa · Sao Tome (Africa), Country: Sao Tome

Dental caries (later in life) · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western… · Later in life, Outpatient care in Western industrialized (European/Anglo-Saxon) countries

Study-specific disease-state discrimination · Oral microbiome samples in 15 case-controlled studies · Human oral samples

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · cold CHX vs cold CPC; operator level

Molar caries detection accuracy · Dental images of human beings · Korea, Lee et al., 2018; CNN

Cost effectiveness · School children (aged 4 to 15 years), primary and secondary schools in the UK and India

Caries experience - % dft (descriptive), primary dentition · CL/P vs no CL/P; Table 4 (1 group/1 study)

Time to initial pain relief (minutes) · Adults (>18 years) with established dry socket following permanent tooth extraction · Initial pain relief

Sensitivity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · General dental practice; in vitro (extracted teeth) and in vivo (clinical) studies, Analysis 2: network meta-analysis (all studies evaluating >=2 index tests)

Adverse events · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China)

Treatment failure (annual failure rate) · Children with severely decayed maxillary primary incisors treated by pulpectomy (non-vital pulp therapy) · 1 year, University, Iran (Eshghi et al. 2013), Reverse metal post (RMP) arm

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · operator level

Contribution to total daily fluoride intake · Adults · Multiple countries, Poor fluoride in water (<0.3 mg/L)

Caries experience · European adolescents aged 16 years · Europe, Exact age

Cost implications · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age · 3-4 months

Clinical and radiographic success rate (>=6 months) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure · >=6 months, Clinical (endodontic/dental), Symptomatic irreversible pulpitis

Clinical attachment level (CAL) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age · 3-4 months

Dentinal caries in permanent (newly erupted) teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of… · 7-year follow-up, Cohort study, Norway (Saethre-Sundli 2020), Enamel caries in primary dentition

Occlusal caries detection accuracy · Dental images of human beings · Switzerland, Casalegno et al., 2018; CNN

Proportion of children with treated/untreated caries (receipt of dental care) · School children, primary schools in the USA · mean 8 months

Additional physical symptoms · People aged 12 years and over with painful TMD lasting 3 months or longer

Early childhood caries (ECC) - association at lead SNP rs74470773 (3:33958083; nearest gene(s) PDCD6IP) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), Population/community child cohorts: rural Appalachia (West Virginia, Pennsylvania) and Iowa (USA) and South West England; European / European non-Hispanic ancestry only, rs74470773 (3:33958083); effect/non-effect allele T/C; MAF 0.47; direction across 5 cohorts -----

Occlusal caries detection accuracy · Dental images of human beings · in-vitro dental images, Moutselos et al., 2019; MASK R-CNN; most common class

Caries prevalence · 12-year-old children (permanent dentition) in Africa · African urban settings, Setting: Urban

MRONJ (incidence rate: cases per patient-year) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ) · mean 28.8 months

Restoration failure · Children with carious primary teeth · 4 years, University, ART; Class I

Dental caries experience · Children and adolescents (<18 years) living with HIV (CLWH) · Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries

Progression of non-cavitated enamel caries · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric…

Difference in summary specificity (NMA, Analysis 2) · Fluorescence vs Visual

Persistent parotid enlargement prevalence · Children and adolescents (<18 years) living with HIV (CLWH) · Hospitals and AIDS outpatient centres in India, Brazil, and several Asian countries

Dental caries (association with sugary drinks/sweets consumption) · Children (deciduous and/or permanent dentition) in low- and middle-income countries · Low- and middle-income countries (Brazil, Nigeria, Cambodia, Tanzania, Mexico, Ethiopia)

Occlusal caries detection accuracy · Dental images of human beings · in-vitro dental images, Moutselos et al., 2019; MASK R-CNN; center pixel class

Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy) · 1 year, University, Turkey (Sonmez and Duruturk 2010), Preformed metal crown (PMC) arm

Progression of non-cavitated enamel caries · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,…

Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars) · Follow-up: median 7 days

Restoration failure · Children with carious primary teeth · 3 years, School setting, ART; Class II

Caries prevalence · 12-year-old children (permanent dentition) in Africa · Malawi (Africa), Country: Malawi

Fibrinogen · People with periodontitis and metabolic syndrome (no CVD; primary prevention) · 12 months

Dental caries severity (median DMFT/dmft/DMFS/dmfs) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal)

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars) · Follow-up: median 7 days

Radiological failure (periapical radiolucency) after at least 1 year · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without… · At least 1 year (range 1 to 5 years)

Caries experience (mean DMFS) · European adolescents aged 12–19 years · Europe (community, subnational and national dental surveys), Region: non-Scandinavian

Restorative index (RI = f/[d+f]) in the primary dentition · Children in the primary dentition with non-syndromic cleft lip and/or palate (CL/P) and comparable children without CL/P · Children with CL/P and comparable non-CL/P children across 12 countries (India, Brazil, China, Sweden, UK, USA, Germany, Greece, Ireland, Netherlands, Jordan, Thailand); studies published 1989-2021

Specificity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · General dental practice; in vitro (extracted teeth) and in vivo (clinical) studies, Analysis 1: fully within-person comparison (studies evaluating >=3 index tests)

Psychological distress at treatment completion · People aged 12 years and over with painful TMD lasting 3 months or longer · Treatment completion

Development of endocarditis (in those with definite indication for prophylaxis) · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive… · within 180 days, Definite indication for prophylaxis

Dental attendance at general dentist · School children, secondary school in the UK (aged 11 to 13 years) · mean 8 months

Caries severity (mean DMFT) · 12-year-old children (permanent dentition) in Africa · Malawi (Africa), Country: Malawi

Tooth loss · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive…

Pulpal disease (signs/symptoms of pulp necrosis) · Children with dentine caries in primary and permanent teeth · 12 months, 3 studies (primary and permanent teeth)